Peg-intron and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Peg-intron (peginterferon alfa-2b), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Rebetol, and have Hepatitis c.

The phase IV clinical study analyzes which people have Sciatica when taking Peg-intron. It is created by eHealthMe based on reports of 11,138 people who have side effects when taking Peg-intron from the FDA, and is updated regularly.

What is Peg-intron?

Peg-intron has active ingredients of peginterferon alfa-2b. eHealthMe is studying from 11,142 Peg-intron users. Check the latest studies of Peg-intron.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,149 drugs and 1,415 conditions by eHealthMe. Check the latest studies of Sciatica.



On Nov, 25, 2025

11,138 people reported to have side effects when taking Peg-intron.
Among them, 27 people (0.24%) have Sciatica.

Could Peg-intron cause Sciatica?

Among these 27 people:

How long have people been on Peg-intron when they have Sciatica? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 95.45 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 4.55 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Sciatica when taking Peg-intron? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Sciatica when taking Peg-intron? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 56 %
  • 50-59: 12 %
  • 60+: 32 %

What are other drugs people take besides Peg-intron? *

  1. Rebetol: 23 people, 85.19%
  2. Zoloft: 13 people, 48.15%
  3. Celexa: 13 people, 48.15%
  4. Folic Acid: 13 people, 48.15%
  5. Norflex: 13 people, 48.15%
  6. Dalmane: 11 people, 40.74%
  7. Norco: 8 people, 29.63%
  8. Zyprexa: 7 people, 25.93%
  9. Anaprox: 7 people, 25.93%
  10. Cephalexin: 7 people, 25.93%

What are other side effects people have besides Sciatica? *

  1. Weakness: 15 people, 55.56%
  2. Depression: 15 people, 55.56%
  3. Influenza Like Illness: 14 people, 51.85%
  4. Pain In Extremity: 14 people, 51.85%
  5. Pain: 13 people, 48.15%
  6. Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 13 people, 48.15%
  7. Balance Disorder: 13 people, 48.15%
  8. Hair Loss: 13 people, 48.15%
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 13 people, 48.15%
  10. Coughing Up Blood: 13 people, 48.15%

What are the existing conditions these people have? *

  1. Hepatitis C: 26 people, 96.30%
  2. Osteoporosis (bones weak and more likely to break): 1 person, 3.70%
  3. Hot Flush (sudden feelings of heat): 1 person, 3.70%
  4. Breast Cancer: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Peg-intron and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Peg-intron:

Sciatica treatments and more:

How severe was Sciatica and when was it recovered:

Expand to all the drugs that have ingredients of peginterferon alfa-2b:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Peg-intron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Browse all the conditions that are associated with Sciatica:


How the study uses the data?

The study uses data from the FDA. It is based on peginterferon alfa-2b (the active ingredients of Peg-intron) and Peg-intron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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