Pegasys and Bi-polar - a phase IV clinical study of FDA data

Summary:

Bi-polar is reported as a side effect among people who take Pegasys (peginterferon alfa 2a), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Copegus, and have Depression.

The phase IV clinical study analyzes which people have Bi-polar when taking Pegasys. It is created by eHealthMe based on reports of 57,338 people who have side effects when taking Pegasys from the FDA, and is updated regularly.

What is Pegasys?

Pegasys has active ingredients of peginterferon alfa 2a. It is often used in hepatitis c. eHealthMe is studying from 57,446 Pegasys users. Check the latest studies of Pegasys.

What is Bi-polar?

Bi-polar is found to be associated with 886 drugs and 1,211 conditions by eHealthMe. Check the latest studies of Bi-polar.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

57,338 people reported to have side effects when taking Pegasys.
Among them, 59 people (0.1%) have Bi-polar.

Among these 59 people:

How long have people been on Pegasys when they have Bi-polar? *

What is the gender of people who have Bi-polar when taking Pegasys? *

female: 72.41 %
male: 27.59 %

What is the age of people who have Bi-polar when taking Pegasys? *

What are other drugs people take besides Pegasys? *

What are other side effects people have besides Bi-polar? *

Depression: 15 people, 25.42%
Fatigue (feeling of tiredness): 13 people, 22.03%
Nausea (feeling of having an urge to vomit): 12 people, 20.34%
Insomnia (sleeplessness): 12 people, 20.34%
Suicidal Ideation: 12 people, 20.34%
Anaemia (lack of blood): 10 people, 16.95%
Irritability: 9 people, 15.25%
Nausea And Vomiting: 8 people, 13.56%
Influenza Like Illness: 8 people, 13.56%
Itching: 8 people, 13.56%

What are the existing conditions these people have? *

Nervousness: 4 people, 6.78%
Depression: 4 people, 6.78%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 5.08%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 5.08%
Stress And Anxiety: 2 people, 3.39%
Sleep Disorder: 2 people, 3.39%
Hiv Infection: 1 person, 1.69%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 1.69%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 1.69%
Diabetes: 1 person, 1.69%

* Approximation only. Some reports may have incomplete information.

Do you take Pegasys and have Bi-polar?

- Check whether Bi-polar is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pegasys:

Pegasys (57,446 reports)

Bi-polar treatments and more:

Bi-polar (109,430 reports)

Browse all side effects of Pegasys:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bi-polar:

Bi-polar (886 drugs)

Browse all the conditions that are associated with Bi-polar:

Bi-polar (1,211 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on peginterferon alfa 2a (the active ingredients of Pegasys) and Pegasys (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.