Pegintron and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Pegintron (peginterferon alfa-2b), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Rebetol, and have Itching.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Pegintron. It is created by eHealthMe based on reports of 10,295 people who have side effects when taking Pegintron from the FDA, and is updated regularly.

What is Pegintron?

Pegintron has active ingredients of peginterferon alfa-2b. It is often used in hepatitis c. eHealthMe is studying from 10,326 Pegintron users. Check the latest studies of Pegintron.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,053 drugs and 1,415 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.



On Oct, 26, 2025

10,295 people reported to have side effects when taking Pegintron.
Among them, 25 people (0.24%) have Hyperthyroidism.

Could Pegintron cause Hyperthyroidism?

Among these 25 people:

How long have people been on Pegintron when they have Hyperthyroidism? *

  • < 1 month: 42.11 %
  • 1 - 6 months: 47.37 %
  • 6 - 12 months: 10.53 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperthyroidism when taking Pegintron? *

  • female: 57.14 %
  • male: 42.86 %

What is the age of people who have Hyperthyroidism when taking Pegintron? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5 %
  • 40-49: 50 %
  • 50-59: 25 %
  • 60+: 20 %

What are other drugs people take besides Pegintron? *

  1. Rebetol: 15 people, 60.00%
  2. Crestor: 7 people, 28.00%
  3. Solu-Medrol: 3 people, 12.00%
  4. Yervoy: 2 people, 8.00%
  5. Pegasys: 2 people, 8.00%
  6. Cefazolin: 2 people, 8.00%
  7. Voltaren: 1 person, 4.00%
  8. Prozac: 1 person, 4.00%
  9. Felodipine: 1 person, 4.00%
  10. Enalapril Maleate: 1 person, 4.00%

What are other side effects people have besides Hyperthyroidism? *

  1. Hyperbilirubinaemia (excess of bilirubin in the blood): 8 people, 32.00%
  2. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 32.00%
  3. Malaise (a feeling of general discomfort or uneasiness): 8 people, 32.00%
  4. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 32.00%
  5. Renal Impairment (severely reduced kidney function): 7 people, 28.00%
  6. Cellulitis (infection under the skin): 7 people, 28.00%
  7. Hepatitis Fulminant (life-threatening condition defined by significantly impaired liver function): 7 people, 28.00%
  8. Pancreatitis Acute (sudden inflammation of pancreas): 7 people, 28.00%
  9. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 7 people, 28.00%
  10. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 7 people, 28.00%

What are the existing conditions these people have? *

  1. Itching: 6 people, 24.00%
  2. Dyslipidaemia (abnormal amount of lipids): 4 people, 16.00%
  3. Fever: 3 people, 12.00%
  4. Rash Pruritic (redness with itching): 2 people, 8.00%
  5. Malignant Melanoma (skin cancer rises from melancytes): 2 people, 8.00%
  6. Stress And Anxiety: 1 person, 4.00%
  7. Rashes (redness): 1 person, 4.00%
  8. Nausea (feeling of having an urge to vomit): 1 person, 4.00%
  9. Migraine (headache): 1 person, 4.00%
  10. Insomnia (sleeplessness): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Pegintron and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pegintron:

Hyperthyroidism treatments and more:

How severe was Hyperthyroidism and when was it recovered:

Expand to all the drugs that have ingredients of peginterferon alfa-2b:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pegintron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Browse all the conditions that are associated with Hyperthyroidism:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on peginterferon alfa-2b (the active ingredients of Pegintron) and Pegintron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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