Pegintron and Hyponatraemia aggravated - a phase IV clinical study of FDA data

Summary:

Hyponatraemia aggravated is reported as a side effect among people who take Pegintron (peginterferon alfa-2b), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Rebetol, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyponatraemia aggravated when taking Pegintron. It is created by eHealthMe based on reports of 10,295 people who have side effects when taking Pegintron from the FDA, and is updated regularly.

What is Pegintron?

Pegintron has active ingredients of peginterferon alfa-2b. It is often used in hepatitis c. eHealthMe is studying from 10,326 Pegintron users. Check the latest studies of Pegintron.

What is Hyponatraemia aggravated?

Hyponatraemia aggravated (abnormally low concentrations of sodium ions in the circulating blood) is found to be associated with 1,498 drugs and 543 conditions by eHealthMe. Check the latest studies of Hyponatraemia aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

10,295 people reported to have side effects when taking Pegintron.
Among them, 15 people (0.15%) have Hyponatraemia aggravated.

Could Pegintron cause Hyponatraemia aggravated?

Among these 15 people:

How long have people been on Pegintron when they have Hyponatraemia aggravated? *

  • < 1 month: 20 %
  • 1 - 6 months: 70 %
  • 6 - 12 months: 10 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyponatraemia aggravated when taking Pegintron? *

  • female: 40 %
  • male: 60 %

What is the age of people who have Hyponatraemia aggravated when taking Pegintron? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.69 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 46.15 %
  • 60+: 46.15 %

What are other drugs people take besides Pegintron? *

  1. Rebetol: 11 people, 73.33%
  2. Victrelis: 3 people, 20.00%
  3. Famotidine: 3 people, 20.00%
  4. Furosemide: 2 people, 13.33%
  5. Flexeril: 2 people, 13.33%
  6. Norvasc: 2 people, 13.33%
  7. Zoloft: 1 person, 6.67%
  8. Crestor: 1 person, 6.67%
  9. Janumet: 1 person, 6.67%
  10. Cyclobenzaprine Hydrochloride: 1 person, 6.67%

What are other side effects people have besides Hyponatraemia aggravated? *

  1. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 33.33%
  2. Nausea And Vomiting: 4 people, 26.67%
  3. Nausea (feeling of having an urge to vomit): 4 people, 26.67%
  4. Leukopenia (less number of white blood cells in blood): 3 people, 20.00%
  5. Weight Decreased: 3 people, 20.00%
  6. Weakness: 3 people, 20.00%
  7. Dehydration (dryness resulting from the removal of water): 3 people, 20.00%
  8. Anaemia (lack of blood): 3 people, 20.00%
  9. Malaise (a feeling of general discomfort or uneasiness): 3 people, 20.00%
  10. Fall: 2 people, 13.33%

What are the existing conditions these people have? *

  1. High Blood Pressure: 3 people, 20.00%
  2. Abdominal Discomfort: 2 people, 13.33%
  3. Oedema (fluid collection in tissue): 1 person, 6.67%
  4. Infection: 1 person, 6.67%
  5. Indigestion: 1 person, 6.67%
  6. Hepatitis C Virus Test Positive: 1 person, 6.67%
  7. Gastritis (inflammation of stomach): 1 person, 6.67%
  8. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Pegintron and have Hyponatraemia aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pegintron:

Hyponatraemia aggravated treatments and more:

How severe was Hyponatraemia aggravated and when was it recovered:

Expand to all the drugs that have ingredients of peginterferon alfa-2b:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pegintron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyponatraemia aggravated:

Browse all the conditions that are associated with Hyponatraemia aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on peginterferon alfa-2b (the active ingredients of Pegintron) and Pegintron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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