Pemetrexed and Hyponatremia - a phase IV clinical study of FDA data
Summary:
Hyponatremia is reported as a side effect among people who take Pemetrexed (pemetrexed), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Folic Acid, and have Lung cancer - non-small cell.
The phase IV clinical study analyzes which people have Hyponatremia when taking Pemetrexed. It is created by eHealthMe based on reports of 17,478 people who have side effects when taking Pemetrexed from the FDA, and is updated regularly.
What is Pemetrexed?
Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.
What is Hyponatremia?
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration) is found to be associated with 1,937 drugs and 2,272 conditions by eHealthMe. Check the latest studies of Hyponatremia.
17,478 people reported to have side effects when taking Pemetrexed.
Among them, 196 people (1.12%) have Hyponatremia.

Among these 196 people:
How long have people been on Pemetrexed when they have Hyponatremia? *
What is the gender of people who have Hyponatremia when taking Pemetrexed? *
What is the age of people who have Hyponatremia when taking Pemetrexed? *
What are other drugs people take besides Pemetrexed? *
What are other side effects people have besides Hyponatremia? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Pemetrexed and have Hyponatremia?
- Check whether Hyponatremia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Pemetrexed:
- Pemetrexed (17,491 reports)
Hyponatremia treatments and more:
- Hyponatremia (72,436 reports)
How severe was Hyponatremia and when was it recovered:
Expand to all the drugs that have ingredients of pemetrexed:
- Hyponatremia and drugs with ingredients of pemetrexed (253 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pemetrexed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hyponatremia:
- Hyponatremia (1,937 drugs)
Browse all the conditions that are associated with Hyponatremia:
- Hyponatremia (2,272 conditions)
Related publications that referenced our studies
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
- Koza Y, Ta? MH, ?im?ek Z, Gündo?du F, "Hyponatremia and heart failure: the overlooked piece of the puzzle", Anatolian journal of cardiology, 2016 Jan .
- Das S, Bandyopadhyay S, Ramasamy A, Prabhu VV, Pachiappan S, "A case of losartan-induced severe hyponatremia", Journal of pharmacology & pharmacotherapeutics, 2015 Jan .
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Kate N, Grover S, Kumar S, Modi M, "Bupropion-induced hyponatremia", General hospital psychiatry, 2013 Dec .
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
- Koza Y, Ta? MH, ?im?ek Z, Gündo?du F, "Hyponatremia and heart failure: the overlooked piece of the puzzle", Anatolian journal of cardiology, 2016 Jan .
- Das S, Bandyopadhyay S, Ramasamy A, Prabhu VV, Pachiappan S, "A case of losartan-induced severe hyponatremia", Journal of pharmacology & pharmacotherapeutics, 2015 Jan .
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Kate N, Grover S, Kumar S, Modi M, "Bupropion-induced hyponatremia", General hospital psychiatry, 2013 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on pemetrexed (the active ingredients of Pemetrexed) and Pemetrexed (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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