Pentacarinat and Hyponatraemia aggravated - a phase IV clinical study of FDA data

Summary:

Hyponatraemia aggravated is reported as a side effect among people who take Pentacarinat (pentamidine isethionate), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Cyclophosphamide, and have Fever.

The phase IV clinical study analyzes which people have Hyponatraemia aggravated when taking Pentacarinat. It is created by eHealthMe based on reports of 1,546 people who have side effects when taking Pentacarinat from the FDA, and is updated regularly.

What is Pentacarinat?

Pentacarinat has active ingredients of pentamidine isethionate. eHealthMe is studying from 1,546 Pentacarinat users. Check the latest studies of Pentacarinat.

What is Hyponatraemia aggravated?

Hyponatraemia aggravated (abnormally low concentrations of sodium ions in the circulating blood) is found to be associated with 1,510 drugs and 543 conditions by eHealthMe. Check the latest studies of Hyponatraemia aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

1,546 people reported to have side effects when taking Pentacarinat.
Among them, 25 people (1.62%) have Hyponatraemia aggravated.

Could Pentacarinat cause Hyponatraemia aggravated?

Among these 25 people:

How long have people been on Pentacarinat when they have Hyponatraemia aggravated? *

What is the gender of people who have Hyponatraemia aggravated when taking Pentacarinat? *

female: 27.27 %
male: 72.73 %

What is the age of people who have Hyponatraemia aggravated when taking Pentacarinat? *

What are other drugs people take besides Pentacarinat? *

Acetylsalicylic Acid: 7 people, 28.00%
Cyclophosphamide: 7 people, 28.00%
Daptomycin: 6 people, 24.00%
Valacyclovir: 5 people, 20.00%
Levetiracetam: 5 people, 20.00%
Paroxetine: 5 people, 20.00%
Acetaminophen: 4 people, 16.00%
Fludarabine Phosphate: 4 people, 16.00%
Meropenem: 4 people, 16.00%
Valacyclovir Hydrochloride: 3 people, 12.00%

What are other side effects people have besides Hyponatraemia aggravated? *

Arrhythmias (irregular heartbeat): 8 people, 32.00%
Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 7 people, 28.00%
Urinary Tract Infection: 7 people, 28.00%
Pneumonia: 7 people, 28.00%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 7 people, 28.00%
Inappropriate Antidiuretic Hormone Secretion: 7 people, 28.00%
Nocardia Infection (a bacterial infection that usually starts in the lungs. it may spread to other organ systems): 7 people, 28.00%
Mycobacterium Fortuitum Infection (bacterial infection): 7 people, 28.00%
Herpes Simplex (herpes simplex is a common viral infection): 7 people, 28.00%
Genitourinary Tract Infection (infection of genital tract and urinary tract): 7 people, 28.00%

What are the existing conditions these people have? *

Infection: 6 people, 24.00%
Diffuse Large B-Cell Lymphoma Refractory (cancer of b cells, a type of white blood cell-relapsed): 6 people, 24.00%
Bone Marrow Conditioning Regimen: 6 people, 24.00%
Fever: 6 people, 24.00%
Immunodeficiency Disorders: 4 people, 16.00%
Insomnia (sleeplessness): 3 people, 12.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 12.00%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 3 people, 12.00%
Pain: 3 people, 12.00%
Stress And Anxiety: 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

Do you take Pentacarinat and have Hyponatraemia aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pentacarinat:

Pentacarinat (1,546 reports)

Browse all side effects of Pentacarinat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyponatraemia aggravated:

Hyponatraemia aggravated (1,510 drugs)

Browse all the conditions that are associated with Hyponatraemia aggravated:

Hyponatraemia aggravated (543 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pentamidine isethionate (the active ingredients of Pentacarinat) and Pentacarinat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.