Pentam and Fluid retention - a phase IV clinical study of FDA data

Summary:

Fluid retention is reported as a side effect among people who take Pentam (pentamidine isethionate), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Acyclovir, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Fluid retention when taking Pentam. It is created by eHealthMe based on reports of 5,677 people who have side effects when taking Pentam from the FDA, and is updated regularly.

What is Pentam?

Pentam has active ingredients of pentamidine isethionate. eHealthMe is studying from 5,686 Pentam users. Check the latest studies of Pentam.

What is Fluid retention?

Fluid retention (an abnormal accumulation of fluid in the blood) is found to be associated with 1,702 drugs and 2,444 conditions by eHealthMe. Check the latest studies of Fluid retention.

On Jul, 05, 2026

5,677 people reported to have side effects when taking Pentam.
Among them, 15 people (0.26%) have Fluid retention.

Among these 15 people:

How long have people been on Pentam when they have Fluid retention? *

What is the gender of people who have Fluid retention when taking Pentam? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Fluid retention when taking Pentam? *

What are other drugs people take besides Pentam? *

What are other side effects people have besides Fluid retention? *

Fever: 7 people, 46.67%
Weakness: 5 people, 33.33%
Back Pain: 5 people, 33.33%
Oedema Peripheral (superficial swelling): 5 people, 33.33%
Abdominal Distension: 4 people, 26.67%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 26.67%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 26.67%
Blood Bilirubin Increased: 4 people, 26.67%
Hypotension (abnormally low blood pressure): 4 people, 26.67%
Stress And Anxiety: 4 people, 26.67%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 4 people, 26.67%
High Blood Pressure: 3 people, 20.00%
Rashes (redness): 2 people, 13.33%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 2 people, 13.33%
Cardiac Disorder: 2 people, 13.33%
Blood Uric Acid Increased: 2 people, 13.33%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 13.33%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 6.67%
Insomnia (sleeplessness): 1 person, 6.67%
Hiv Infection: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Pentam and have Fluid retention?

- Check whether Fluid retention is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pentam:

Pentam (5,686 reports)

Fluid retention treatments and more:

Fluid retention (79,660 reports)

Browse all side effects of Pentam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fluid retention:

Fluid retention (1,702 drugs)

Browse all the conditions that are associated with Fluid retention:

Fluid retention (2,444 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pentamidine isethionate (the active ingredients of Pentam) and Pentam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.