Pentasa and Autoimmune disorder - a phase IV clinical study of FDA data

Summary:

Autoimmune disorder is reported as a side effect among people who take Pentasa (mesalamine), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Remicade, and have Diarrhea.

The phase IV clinical study analyzes which people have Autoimmune disorder when taking Pentasa. It is created by eHealthMe based on reports of 22,797 people who have side effects when taking Pentasa from the FDA, and is updated regularly.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 23,325 Pentasa users. Check the latest studies of Pentasa.

What is Autoimmune disorder?

Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue) is found to be associated with 718 drugs and 825 conditions by eHealthMe. Check the latest studies of Autoimmune disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

22,797 people reported to have side effects when taking Pentasa.
Among them, 16 people (0.07%) have Autoimmune disorder.

Could Pentasa cause Autoimmune disorder?

Among these 16 people:

How long have people been on Pentasa when they have Autoimmune disorder? *

What is the gender of people who have Autoimmune disorder when taking Pentasa? *

female: 93.75 %
male: 6.25 %

What is the age of people who have Autoimmune disorder when taking Pentasa? *

What are other drugs people take besides Pentasa? *

What are other side effects people have besides Autoimmune disorder? *

Fever: 6 people, 37.50%
Joint Pain: 6 people, 37.50%
Thrombocytopenia (decrease of platelets in blood): 4 people, 25.00%
Fatigue (feeling of tiredness): 4 people, 25.00%
Weight Decreased: 4 people, 25.00%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 3 people, 18.75%
Leukopenia (less number of white blood cells in blood): 3 people, 18.75%
Pain: 3 people, 18.75%
Indigestion: 3 people, 18.75%
Headache (pain in head): 3 people, 18.75%

What are the existing conditions these people have? *

Sleep Disorder: 2 people, 12.50%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 12.50%
Premature Labor: 2 people, 12.50%
Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 2 people, 12.50%
Iridocyclitis (inflammation of the iris and ciliary body of the eye): 2 people, 12.50%
Inflammatory Bowel Disease: 2 people, 12.50%
Indigestion: 2 people, 12.50%
Hypersensitivity: 2 people, 12.50%
H1n1 Influenza (flu (influenza), which is caused by virus influenza a (h1n1)): 2 people, 12.50%
Diarrhea: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Pentasa and have Autoimmune disorder?

- Check whether Autoimmune disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pentasa:

Pentasa (23,325 reports)

Browse all side effects of Pentasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Autoimmune disorder:

Autoimmune disorder (718 drugs)

Browse all the conditions that are associated with Autoimmune disorder:

Autoimmune disorder (825 conditions)

Related publications that referenced our studies

Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on mesalamine (the active ingredients of Pentasa) and Pentasa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.