Pentasa and Sedation - a phase IV clinical study of FDA data

Summary:

Sedation is reported as a side effect among people who take Pentasa (mesalamine), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Tylenol, and have Headache.

The phase IV clinical study analyzes which people have Sedation when taking Pentasa. It is created by eHealthMe based on reports of 22,797 people who have side effects when taking Pentasa from the FDA, and is updated regularly.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 23,326 Pentasa users. Check the latest studies of Pentasa.

What is Sedation?

Sedation is found to be associated with 1,309 drugs and 1,290 conditions by eHealthMe. Check the latest studies of Sedation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

22,797 people reported to have side effects when taking Pentasa.
Among them, 23 people (0.1%) have Sedation.

Among these 23 people:

How long have people been on Pentasa when they have Sedation? *

What is the gender of people who have Sedation when taking Pentasa? *

female: 47.06 %
male: 52.94 %

What is the age of people who have Sedation when taking Pentasa? *

What are other drugs people take besides Pentasa? *

What are other side effects people have besides Sedation? *

Fatigue (feeling of tiredness): 11 people, 47.83%
Anaemia (lack of blood): 9 people, 39.13%
Diarrhea: 9 people, 39.13%
Dizziness: 9 people, 39.13%
Weight Increased: 8 people, 34.78%
Poor Quality Sleep: 8 people, 34.78%
Blood Pressure Fluctuation: 8 people, 34.78%
Chlamydial Infection (a common sexually transmitted infection (sti) in humans caused by the bacterium chlamydia trachomatis): 8 people, 34.78%
Concussion (short loss of normal brain function in response to a head injury): 8 people, 34.78%
Cough: 8 people, 34.78%

What are the existing conditions these people have? *

Headache (pain in head): 9 people, 39.13%
Anaemia (lack of blood): 8 people, 34.78%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 4.35%
Stress And Anxiety: 1 person, 4.35%
Osteoporosis (bones weak and more likely to break): 1 person, 4.35%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 4.35%
Multiple Allergies (allergy to multiple agents): 1 person, 4.35%
Itching: 1 person, 4.35%
High Blood Cholesterol: 1 person, 4.35%
Diabetes: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Pentasa and have Sedation?

- Check whether Sedation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pentasa:

Pentasa (23,326 reports)

Sedation treatments and more:

Sedation (52,223 reports)

Browse all side effects of Pentasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sedation:

Sedation (1,309 drugs)

Browse all the conditions that are associated with Sedation:

Sedation (1,290 conditions)

Related publications that referenced our studies

Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on mesalamine (the active ingredients of Pentasa) and Pentasa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.