Pentazocine and Pleural effusion - a phase IV clinical study of FDA data

Summary:

Pleural effusion is reported as a side effect among people who take Pentazocine (pentazocine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Polaramine, and have Diarrhea.

The phase IV clinical study analyzes which people have Pleural effusion when taking Pentazocine. It is created by eHealthMe based on reports of 734 people who have side effects when taking Pentazocine from the FDA, and is updated regularly.

What is Pentazocine?

Pentazocine has active ingredients of pentazocine hydrochloride. eHealthMe is studying from 741 Pentazocine users. Check the latest studies of Pentazocine.

What is Pleural effusion?

Pleural effusion (water on the lungs) is found to be associated with 2,219 drugs and 3,150 conditions by eHealthMe. Check the latest studies of Pleural effusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

734 people reported to have side effects when taking Pentazocine.
Among them, 17 people (2.32%) have Pleural effusion.

Could Pentazocine cause Pleural effusion?

Among these 17 people:

How long have people been on Pentazocine when they have Pleural effusion? *

What is the gender of people who have Pleural effusion when taking Pentazocine? *

female: 88.89 %
male: 11.11 %

What is the age of people who have Pleural effusion when taking Pentazocine? *

What are other drugs people take besides Pentazocine? *

Xylocaine: 13 people, 76.47%
Polaramine: 13 people, 76.47%
Cefazolin Sodium: 8 people, 47.06%
Famotidine: 8 people, 47.06%
Lyrica: 8 people, 47.06%
Potassium Aspartate: 8 people, 47.06%
Amoxicillin: 8 people, 47.06%
Dexamethasone Sodium Phosphate: 8 people, 47.06%
Fexofenadine Hydrochloride: 8 people, 47.06%
Vitamins: 8 people, 47.06%

What are other side effects people have besides Pleural effusion? *

Hypokalemia (low potassium): 15 people, 88.24%
Oedema Peripheral (superficial swelling): 15 people, 88.24%
Cardiac Failure: 13 people, 76.47%
Weakness: 11 people, 64.71%
Constipation: 11 people, 64.71%
Hypotension (abnormally low blood pressure): 9 people, 52.94%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 47.06%
Ventricular Arrhythmia (problem with the rate or rhythm of the heartbeat): 8 people, 47.06%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 47.06%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 47.06%

What are the existing conditions these people have? *

Diarrhea: 13 people, 76.47%
Hypokalemia (low potassium): 12 people, 70.59%
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 8 people, 47.06%
Neuropathy Peripheral (surface nerve damage): 8 people, 47.06%
Vitamin B1 Deficiency: 8 people, 47.06%
Allergic Rhinitis: 8 people, 47.06%
Hypotension (abnormally low blood pressure): 8 people, 47.06%
Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 8 people, 47.06%
Muscle Spasms (muscle contraction): 8 people, 47.06%
Cardiac Failure: 8 people, 47.06%

* Approximation only. Some reports may have incomplete information.

Do you take Pentazocine and have Pleural effusion?

- Check whether Pleural effusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pentazocine:

Pentazocine (741 reports)

Pleural effusion treatments and more:

Pleural effusion (84,634 reports)

Browse all side effects of Pentazocine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pleural effusion:

Pleural effusion (2,219 drugs)

Browse all the conditions that are associated with Pleural effusion:

Pleural effusion (3,150 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pentazocine hydrochloride (the active ingredients of Pentazocine) and Pentazocine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.