Pepcid complete and Agitation - a phase IV clinical study of FDA data

Summary:

Agitation is reported as a side effect among people who take Pepcid complete (calcium carbonate; famotidine; magnesium hydroxide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Copaxone, and have Gait disturbance.

The phase IV clinical study analyzes which people have Agitation when taking Pepcid complete. It is created by eHealthMe based on reports of 2,781 people who have side effects when taking Pepcid complete from the FDA, and is updated regularly.

What is Pepcid complete?

Pepcid complete has active ingredients of calcium carbonate; famotidine; magnesium hydroxide. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 2,884 Pepcid complete users. Check the latest studies of Pepcid complete.

What is Agitation?

Agitation (state of anxiety or nervous excitement) is found to be associated with 2,283 drugs and 3,318 conditions by eHealthMe. Check the latest studies of Agitation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

2,781 people reported to have side effects when taking Pepcid complete.
Among them, 11 people (0.4%) have Agitation.

Among these 11 people:

How long have people been on Pepcid complete when they have Agitation? *

What is the gender of people who have Agitation when taking Pepcid complete? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Agitation when taking Pepcid complete? *

What are other drugs people take besides Pepcid complete? *

What are other side effects people have besides Agitation? *

Drug Ineffective: 6 people, 54.55%
Dizziness: 6 people, 54.55%
Headache (pain in head): 6 people, 54.55%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 5 people, 45.45%
Fatigue (feeling of tiredness): 4 people, 36.36%
Insomnia (sleeplessness): 4 people, 36.36%
Cough: 3 people, 27.27%
Fever: 3 people, 27.27%
Chills (felling of cold): 3 people, 27.27%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 27.27%

What are the existing conditions these people have? *

Muscle Spasms (muscle contraction): 3 people, 27.27%
Gait Disturbance: 3 people, 27.27%
High Blood Pressure: 2 people, 18.18%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 9.09%
Nausea (feeling of having an urge to vomit): 1 person, 9.09%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
Menopause (end of monthly cycles in women): 1 person, 9.09%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid complete and have Agitation?

- Check whether Agitation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pepcid complete:

Pepcid complete (2,884 reports)

Agitation treatments and more:

Agitation (142,109 reports)

How severe was Agitation and when was it recovered:

Agitation in Pepcid complete

Expand to all the drugs that have ingredients of calcium carbonate; famotidine; magnesium hydroxide:

Agitation and drugs with ingredients of calcium carbonate; famotidine; magnesium hydroxide

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pepcid complete:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Agitation:

Agitation (2,283 drugs)

Browse all the conditions that are associated with Agitation:

Agitation (3,318 conditions)

Related publications that referenced our studies

Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on calcium carbonate; famotidine; magnesium hydroxide (the active ingredients of Pepcid complete) and Pepcid complete (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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