Pepcid rpd and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Pepcid rpd (famotidine), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Kesimpta, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Headache when taking Pepcid rpd. It is created by eHealthMe based on reports of 1,193 people who have side effects when taking Pepcid rpd from the FDA, and is updated regularly.

What is Pepcid rpd?

Pepcid rpd has active ingredients of famotidine. eHealthMe is studying from 1,197 Pepcid rpd users. Check the latest studies of Pepcid rpd.

What is Headache?

Headache (pain in head) is found to be associated with 3,747 drugs and 5,770 conditions by eHealthMe. Check the latest studies of Headache.



On Jul, 10, 2026

1,193 people reported to have side effects when taking Pepcid rpd.
Among them, 12 people (1.01%) have Headache.

Could Pepcid rpd cause Headache?

Among these 12 people:

How long have people been on Pepcid rpd when they have Headache? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Headache when taking Pepcid rpd? *

  • female: 63.64 %
  • male: 36.36 %

What is the age of people who have Headache when taking Pepcid rpd? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 80 %
  • 60+: 20 %

What are other drugs people take besides Pepcid rpd? *

  1. Kesimpta: 6 people, 50.00%
  2. Lasix: 4 people, 33.33%
  3. Vitamin B12: 4 people, 33.33%
  4. Magnesium: 4 people, 33.33%
  5. Gabapentin: 4 people, 33.33%
  6. Diovan: 4 people, 33.33%
  7. Protonix: 3 people, 25.00%
  8. Flonase: 3 people, 25.00%
  9. Aspirin: 3 people, 25.00%
  10. Melatonin: 3 people, 25.00%

What are other side effects people have besides Headache? *

  1. Pain: 4 people, 33.33%
  2. Chills (felling of cold): 4 people, 33.33%
  3. Colitis Ischaemic (due to infection of intestine impaired blood supply to colon): 4 people, 33.33%
  4. Nausea (feeling of having an urge to vomit): 3 people, 25.00%
  5. Abdominal Pain Upper: 3 people, 25.00%
  6. Weakness: 2 people, 16.67%
  7. Fatigue (feeling of tiredness): 2 people, 16.67%
  8. Influenza Like Illness: 2 people, 16.67%
  9. Urinary Tract Infection: 1 person, 8.33%
  10. Head Discomfort: 1 person, 8.33%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 33.33%
  2. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 1 person, 8.33%
  3. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid rpd and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pepcid rpd:

Headache treatments and more:

How severe was Headache and when was it recovered:

Expand to all the drugs that have ingredients of famotidine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pepcid rpd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Browse all the conditions that are associated with Headache:


How the study uses the data?

The study uses data from the FDA. It is based on famotidine (the active ingredients of Pepcid rpd) and Pepcid rpd (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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