Pepcid and Chapped lips - a phase IV clinical study of FDA data

Summary:

Chapped lips is reported as a side effect among people who take Pepcid (famotidine), especially for people who are male, 60+ old, also take Accutane, and have Acne.

The phase IV clinical study analyzes which people have Chapped lips when taking Pepcid. It is created by eHealthMe based on reports of 54,527 people who have side effects when taking Pepcid from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

What is Chapped lips?

Chapped lips (cracking, fissuring, and peeling of the skin f lip) is found to be associated with 423 drugs and 872 conditions by eHealthMe. Check the latest studies of Chapped lips.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

54,527 people reported to have side effects when taking Pepcid.
Among them, 17 people (0.03%) have Chapped lips.

Among these 17 people:

What is the gender of people who have Chapped lips when taking Pepcid? *

female: 25 %
male: 75 %

What is the age of people who have Chapped lips when taking Pepcid? *

What are other drugs people take besides Pepcid? *

What are other side effects people have besides Chapped lips? *

Depression: 9 people, 52.94%
Nausea (feeling of having an urge to vomit): 8 people, 47.06%
Inflammatory Bowel Disease: 8 people, 47.06%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 8 people, 47.06%
Constipation: 8 people, 47.06%
Migraine (headache): 8 people, 47.06%
Stress And Anxiety: 8 people, 47.06%
Small Intestinal Obstruction (blockage in small intestine): 6 people, 35.29%
Pancreatitis (inflammation of pancreas): 6 people, 35.29%
Intestinal Fistula: 6 people, 35.29%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 11.76%
Acne (skin problems that cause pimples): 2 people, 11.76%
Renal Cell Carcinoma (a kidney cancer): 1 person, 5.88%
Peripheral Swelling: 1 person, 5.88%
Ovarian Cancer (cancer of ovary): 1 person, 5.88%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 5.88%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 5.88%
Insomnia (sleeplessness): 1 person, 5.88%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.88%
Gastric Disorder (disease of stomach): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid and have Chapped lips?

- Check whether Chapped lips is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pepcid:

Pepcid (55,774 reports)

Chapped lips treatments and more:

Chapped lips (5,317 reports)

Browse all side effects of Pepcid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chapped lips:

Chapped lips (423 drugs)

Browse all the conditions that are associated with Chapped lips:

Chapped lips (872 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on famotidine (the active ingredients of Pepcid) and Pepcid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.