Pepcid and Hyperacusis - a phase IV clinical study of FDA data

Summary:

Hyperacusis is reported as a side effect among people who take Pepcid (famotidine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin D, and have Immunodeficiency.

The phase IV clinical study analyzes which people have Hyperacusis when taking Pepcid. It is created by eHealthMe based on reports of 54,527 people who have side effects when taking Pepcid from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,775 Pepcid users. Check the latest studies of Pepcid.

What is Hyperacusis?

Hyperacusis (disorder in loudness perception) is found to be associated with 401 drugs and 611 conditions by eHealthMe. Check the latest studies of Hyperacusis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

54,527 people reported to have side effects when taking Pepcid.
Among them, 14 people (0.03%) have Hyperacusis.

Among these 14 people:

How long have people been on Pepcid when they have Hyperacusis? *

What is the gender of people who have Hyperacusis when taking Pepcid? *

female: 100 %
male: 0.0 %

What is the age of people who have Hyperacusis when taking Pepcid? *

What are other drugs people take besides Pepcid? *

Lisinopril: 5 people, 35.71%
Vitamin D: 5 people, 35.71%
Montelukast Sodium: 4 people, 28.57%
Oxycodone Hydrochloride: 4 people, 28.57%
Ondansetron Hydrochloride: 4 people, 28.57%
Omeprazole: 4 people, 28.57%
Nasacort: 4 people, 28.57%
Naproxen: 4 people, 28.57%
Mucinex: 4 people, 28.57%
Magnesium: 4 people, 28.57%

What are other side effects people have besides Hyperacusis? *

Fatigue (feeling of tiredness): 10 people, 71.43%
Nausea (feeling of having an urge to vomit): 7 people, 50.00%
Headache (pain in head): 7 people, 50.00%
Nausea And Vomiting: 6 people, 42.86%
Pain: 6 people, 42.86%
Photophobia (extreme sensitivity to light): 5 people, 35.71%
Anaemia (lack of blood): 5 people, 35.71%
Urinary Tract Infection: 5 people, 35.71%
Neck Pain: 5 people, 35.71%
Infection: 4 people, 28.57%

What are the existing conditions these people have? *

Immunodeficiency: 4 people, 28.57%
Stress And Anxiety: 3 people, 21.43%
Birth Control: 2 people, 14.29%
Pain: 2 people, 14.29%
Headache (pain in head): 2 people, 14.29%
Hypersensitivity: 2 people, 14.29%
Nausea (feeling of having an urge to vomit): 2 people, 14.29%
Chest Pain: 1 person, 7.14%
Constipation: 1 person, 7.14%
Dysmenorrhea (painful menstruation): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid and have Hyperacusis?

- Check whether Hyperacusis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pepcid:

Pepcid (55,775 reports)

Hyperacusis treatments and more:

Hyperacusis (4,388 reports)

Browse all side effects of Pepcid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperacusis:

Hyperacusis (401 drugs)

Browse all the conditions that are associated with Hyperacusis:

Hyperacusis (611 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on famotidine (the active ingredients of Pepcid) and Pepcid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.