Pepcid and Skin tightness - a phase IV clinical study of FDA data

Summary:

Skin tightness is reported as a side effect among people who take Pepcid (famotidine), especially for people who are male, 60+ old, also take Magnevist, and have Nuclear magnetic resonance imaging brain.

The phase IV clinical study analyzes which people have Skin tightness when taking Pepcid. It is created by eHealthMe based on reports of 54,527 people who have side effects when taking Pepcid from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,775 Pepcid users. Check the latest studies of Pepcid.

What is Skin tightness?

Skin tightness is found to be associated with 606 drugs and 607 conditions by eHealthMe. Check the latest studies of Skin tightness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

54,527 people reported to have side effects when taking Pepcid.
Among them, 41 people (0.08%) have Skin tightness.

Among these 41 people:

What is the gender of people who have Skin tightness when taking Pepcid? *

female: 39.02 %
male: 60.98 %

What is the age of people who have Skin tightness when taking Pepcid? *

What are other drugs people take besides Pepcid? *

What are other side effects people have besides Skin tightness? *

Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 35 people, 85.37%
Skin Hypertrophy (skin cells enlarges): 29 people, 70.73%
Oedema Peripheral (superficial swelling): 29 people, 70.73%
Joint Range Of Motion Decreased (disease of joint movement): 28 people, 68.29%
Pain: 25 people, 60.98%
Skin Induration (an abnormally hard spot or area on the skin): 25 people, 60.98%
Rashes (redness): 21 people, 51.22%
Itching: 21 people, 51.22%
Skin Exfoliation (removal of the oldest dead skin cells): 20 people, 48.78%
Mobility Decreased (ability to move is reduced): 19 people, 46.34%

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 19 people, 46.34%
Pain: 10 people, 24.39%
Nuclear Magnetic Resonance Imaging Abdominal: 6 people, 14.63%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 9.76%
Rash Pruritic (redness with itching): 3 people, 7.32%
Stress And Anxiety: 2 people, 4.88%
Pancreatic Mass: 2 people, 4.88%
Multiple Myeloma (cancer of the plasma cells): 2 people, 4.88%
Bile Duct Obstruction (blockage in the tubes that carry bile from the liver to the gallbladder): 2 people, 4.88%
Tumor: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid and have Skin tightness?

- Check whether Skin tightness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pepcid:

Pepcid (55,775 reports)

Skin tightness treatments and more:

Skin tightness (5,694 reports)

Browse all side effects of Pepcid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin tightness:

Skin tightness (606 drugs)

Browse all the conditions that are associated with Skin tightness:

Skin tightness (607 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on famotidine (the active ingredients of Pepcid) and Pepcid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.