Percocet and Subdural haemorrhage - a phase IV clinical study of FDA data

Summary:

Subdural haemorrhage is reported as a side effect among people who take Percocet (acetaminophen; oxycodone hydrochloride), especially for people who are female, 60+ old, also take Celexa, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Subdural haemorrhage when taking Percocet. It is created by eHealthMe based on reports of 116,194 people who have side effects when taking Percocet from the FDA, and is updated regularly.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

What is Subdural haemorrhage?

Subdural haemorrhage (bleeding between the skull and the surface of the brain) is found to be associated with 297 drugs and 456 conditions by eHealthMe. Check the latest studies of Subdural haemorrhage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

116,194 people reported to have side effects when taking Percocet.
Among them, 15 people (0.01%) have Subdural haemorrhage.

Could Percocet cause Subdural haemorrhage?

Among these 15 people:

What is the gender of people who have Subdural haemorrhage when taking Percocet? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Subdural haemorrhage when taking Percocet? *

What are other drugs people take besides Percocet? *

What are other side effects people have besides Subdural haemorrhage? *

Fall: 5 people, 33.33%
Weakness: 3 people, 20.00%
Calculus Bladder (bladder stone): 3 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 20.00%
Subdural Effusion (collection of fluid trapped between the surface of the brain and the outer lining of the brain): 2 people, 13.33%
Subarachnoid Haemorrhage (blood leaks into the space between two membranes that surround the brain): 2 people, 13.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 13.33%
Death: 2 people, 13.33%
Wrist Fracture: 1 person, 6.67%
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function): 1 person, 6.67%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 20.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 13.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 13.33%
Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 2 people, 13.33%
Sleep Disorder: 1 person, 6.67%
Itching: 1 person, 6.67%
Insomnia (sleeplessness): 1 person, 6.67%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Percocet and have Subdural haemorrhage?

- Check whether Subdural haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Percocet:

Percocet (119,838 reports)

Subdural haemorrhage treatments and more:

Subdural haemorrhage (3,178 reports)

How severe was Subdural haemorrhage and when was it recovered:

Subdural haemorrhage in Percocet

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Subdural haemorrhage and drugs with ingredients of acetaminophen; oxycodone hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Percocet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Subdural haemorrhage:

Subdural haemorrhage (297 drugs)

Browse all the conditions that are associated with Subdural haemorrhage:

Subdural haemorrhage (456 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Percocet) and Percocet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.