Peridex and Cardiac failure - a phase IV clinical study of FDA data

Summary:

Cardiac failure is reported as a side effect among people who take Peridex (chlorhexidine gluconate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Coumadin, and have Neoplasm malignant.

The phase IV clinical study analyzes which people have Cardiac failure when taking Peridex. It is created by eHealthMe based on reports of 2,787 people who have side effects when taking Peridex from the FDA, and is updated regularly.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

What is Cardiac failure?

Cardiac failure is found to be associated with 2,058 drugs and 2,213 conditions by eHealthMe. Check the latest studies of Cardiac failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

2,787 people reported to have side effects when taking Peridex.
Among them, 49 people (1.76%) have Cardiac failure.

Among these 49 people:

How long have people been on Peridex when they have Cardiac failure? *

What is the gender of people who have Cardiac failure when taking Peridex? *

female: 77.55 %
male: 22.45 %

What is the age of people who have Cardiac failure when taking Peridex? *

What are other drugs people take besides Peridex? *

What are other side effects people have besides Cardiac failure? *

Pain: 31 people, 63.27%
Pneumonia: 29 people, 59.18%
Injury: 28 people, 57.14%
Deformity (disfigurement): 28 people, 57.14%
Swallowing Difficulty: 28 people, 57.14%
Mitral Valve Incompetence (inefficient heart valve): 27 people, 55.10%
Headache (pain in head): 27 people, 55.10%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 27 people, 55.10%
Dyspnea (difficult or laboured breathing): 27 people, 55.10%
Bone Disorder: 27 people, 55.10%

What are the existing conditions these people have? *

Neoplasm Malignant (cancer tumour): 25 people, 51.02%
Calcium Deficiency (lack of calcium): 24 people, 48.98%
Metastases To Spine (cancer spreads to spine): 24 people, 48.98%
Lung Neoplasm (tumour of lung): 23 people, 46.94%
Insomnia (sleeplessness): 5 people, 10.20%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 10.20%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 10.20%
Stomatitis (inflammation of mucous membrane of mouth): 5 people, 10.20%
Lung Cancer - Non-Small Cell (lung cancer): 5 people, 10.20%
Pain: 4 people, 8.16%

* Approximation only. Some reports may have incomplete information.

Do you take Peridex and have Cardiac failure?

- Check whether Cardiac failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Peridex:

Peridex (2,803 reports)

Cardiac failure treatments and more:

Cardiac failure (147,157 reports)

Browse all side effects of Peridex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac failure:

Cardiac failure (2,058 drugs)

Browse all the conditions that are associated with Cardiac failure:

Cardiac failure (2,213 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Peridex) and Peridex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.