Peridex and Cerebellar atrophy - a phase IV clinical study of FDA data

Summary:

Cerebellar atrophy is reported as a side effect among people who take Peridex (chlorhexidine gluconate), especially for people who are male, 60+ old, also take Zometa, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Cerebellar atrophy when taking Peridex. It is created by eHealthMe based on reports of 2,787 people who have side effects when taking Peridex from the FDA, and is updated regularly.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

What is Cerebellar atrophy?

Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements) is found to be associated with 259 drugs and 102 conditions by eHealthMe. Check the latest studies of Cerebellar atrophy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

2,787 people reported to have side effects when taking Peridex.
Among them, 12 people (0.43%) have Cerebellar atrophy.

Could Peridex cause Cerebellar atrophy?

Among these 12 people:

What is the gender of people who have Cerebellar atrophy when taking Peridex? *

  • female: 25 %
  • male: 75 %

What is the age of people who have Cerebellar atrophy when taking Peridex? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 9.09 %
  • 30-39: 0.0 %
  • 40-49: 9.09 %
  • 50-59: 0.0 %
  • 60+: 81.82 %

What are other drugs people take besides Peridex? *

  1. Zometa: 12 people, 100.00%
  2. Risperdal: 8 people, 66.67%
  3. Levaquin: 8 people, 66.67%
  4. Lanoxin: 8 people, 66.67%
  5. Periostat: 8 people, 66.67%
  6. Digoxin: 7 people, 58.33%
  7. Roxanol: 6 people, 50.00%
  8. Aspirin: 5 people, 41.67%
  9. Furosemide: 4 people, 33.33%
  10. Lisinopril: 4 people, 33.33%

What are other side effects people have besides Cerebellar atrophy? *

  1. Pain: 12 people, 100.00%
  2. Spinal Osteoarthritis (joint cartilage loss in spine): 12 people, 100.00%
  3. Injury: 12 people, 100.00%
  4. Osteonecrosis Of Jaw (death of bone of jaw): 12 people, 100.00%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 12 people, 100.00%
  6. Diarrhea: 12 people, 100.00%
  7. Osteomyelitis (infection of bone): 11 people, 91.67%
  8. Cardiac Failure Congestive: 11 people, 91.67%
  9. Pain In Jaw: 11 people, 91.67%
  10. Hypotension (abnormally low blood pressure): 11 people, 91.67%

What are the existing conditions these people have? *

  1. Breast Cancer Metastatic: 3 people, 25.00%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 16.67%
  3. Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
  4. Hepatitis C: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Peridex and have Cerebellar atrophy?

- Check whether Cerebellar atrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Peridex:

Cerebellar atrophy treatments and more:

How severe was Cerebellar atrophy and when was it recovered:

Expand to all the drugs that have ingredients of chlorhexidine gluconate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Peridex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cerebellar atrophy:

Browse all the conditions that are associated with Cerebellar atrophy:


How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Peridex) and Peridex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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