Peridex and Macule - a phase IV clinical study of FDA data

Summary:

Macule is reported as a side effect among people who take Peridex (chlorhexidine gluconate), especially for people who are female, 40-49 old, also take Lasix, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Macule when taking Peridex. It is created by eHealthMe based on reports of 2,787 people who have side effects when taking Peridex from the FDA, and is updated regularly.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

What is Macule?

Macule (a discoloured spot on the skin) is found to be associated with 301 drugs and 705 conditions by eHealthMe. Check the latest studies of Macule.



On Apr, 10, 2026

2,787 people reported to have side effects when taking Peridex.
Among them, 11 people (0.39%) have Macule.

Could Peridex cause Macule?

Among these 11 people:

What is the gender of people who have Macule when taking Peridex? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Macule when taking Peridex? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 100 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Peridex? *

  1. Zovirax: 11 people, 100.00%
  2. Flexeril: 11 people, 100.00%
  3. Nystatin: 11 people, 100.00%
  4. Neurontin: 11 people, 100.00%
  5. Metoclopramide: 11 people, 100.00%
  6. Lorazepam: 11 people, 100.00%
  7. Zometa: 11 people, 100.00%
  8. Lodine: 11 people, 100.00%
  9. Levaquin: 11 people, 100.00%
  10. Lasix: 11 people, 100.00%

What are other side effects people have besides Macule? *

  1. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 11 people, 100.00%
  2. Neuropathy Peripheral (surface nerve damage): 11 people, 100.00%
  3. Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 11 people, 100.00%
  4. Breast Cancer Recurrent: 11 people, 100.00%
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 100.00%
  6. Catheter Site Haematoma (blood clot at catheter site): 11 people, 100.00%
  7. Myositis (inflammation of the muscles): 11 people, 100.00%
  8. Cystitis Haemorrhagic (blood in the urine and painful voiding): 11 people, 100.00%
  9. Muscle Spasms (muscle contraction): 11 people, 100.00%
  10. Muscle Aches (muscle pain): 11 people, 100.00%

What are the existing conditions these people have? *

  1. Stress And Anxiety: 11 people, 100.00%
  2. Breast Cancer Metastatic: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Peridex and have Macule?

- Check whether Macule is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Peridex:

Macule treatments and more:

How severe was Macule and when was it recovered:

Expand to all the drugs that have ingredients of chlorhexidine gluconate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Peridex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Macule:

Browse all the conditions that are associated with Macule:


How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Peridex) and Peridex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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