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Peridex and Oedema mouth - a phase IV clinical study of FDA data

Summary:

Oedema mouth is reported as a side effect among people who take Peridex (chlorhexidine gluconate), especially for people who are female, 50-59 old, also take Compazine, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Oedema mouth when taking Peridex. It is created by eHealthMe based on reports of 2,787 people who have side effects when taking Peridex from the FDA, and is updated regularly.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

What is Oedema mouth?

Oedema mouth (swelling of mouth) is found to be associated with 536 drugs and 758 conditions by eHealthMe. Check the latest studies of Oedema mouth.

On Jul, 27, 2026

2,787 people reported to have side effects when taking Peridex.
Among them, 16 people (0.57%) have Oedema mouth.

Could Peridex cause Oedema mouth?

Among these 16 people:

What is the gender of people who have Oedema mouth when taking Peridex? *

  • female: 93.75 %
  • male: 6.25 %

What is the age of people who have Oedema mouth when taking Peridex? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12.5 %
  • 50-59: 81.25 %
  • 60+: 6.25 %

What are other drugs people take besides Peridex? *

  1. Zometa: 15 people, 93.75%
  2. Naproxen: 15 people, 93.75%
  3. Compazine: 15 people, 93.75%
  4. Soma: 14 people, 87.50%
  5. Neurontin: 14 people, 87.50%
  6. Zofran: 14 people, 87.50%
  7. Femara: 14 people, 87.50%
  8. Faslodex: 14 people, 87.50%
  9. Colace: 14 people, 87.50%
  10. Septra Ds: 14 people, 87.50%

What are other side effects people have besides Oedema mouth? *

  1. Osteonecrosis Of Jaw (death of bone of jaw): 16 people, 100.00%
  2. Oral Pain: 16 people, 100.00%
  3. Weakness: 15 people, 93.75%
  4. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 15 people, 93.75%
  5. Emotional Distress: 15 people, 93.75%
  6. Osteopenia (a condition where bone mineral density is lower than normal): 15 people, 93.75%
  7. Dental Caries: 15 people, 93.75%
  8. Rib Fracture: 15 people, 93.75%
  9. Scoliosis (a medical condition in which a person's spine is curved from side to side): 15 people, 93.75%
  10. Spinal Osteoarthritis (joint cartilage loss in spine): 15 people, 93.75%

What are the existing conditions these people have? *

  1. Stress And Anxiety: 14 people, 87.50%
  2. Breast Cancer Metastatic: 7 people, 43.75%
  3. Osteoporosis (bones weak and more likely to break): 1 person, 6.25%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.25%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Peridex and have Oedema mouth?

- Check whether Oedema mouth is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Peridex:

Oedema mouth treatments and more:

How severe was Oedema mouth and when was it recovered:

Expand to all the drugs that have ingredients of chlorhexidine gluconate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Peridex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema mouth:

Browse all the conditions that are associated with Oedema mouth:

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Peridex) and Peridex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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