Periogard and Weight fluctuation - a phase IV clinical study of FDA data

Summary:

Weight fluctuation is reported as a side effect among people who take Periogard (chlorhexidine gluconate), especially for people who are female, 40-49 old, also take Glucosamine, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Weight fluctuation when taking Periogard. It is created by eHealthMe based on reports of 3,812 people who have side effects when taking Periogard from the FDA, and is updated regularly.

What is Periogard?

Periogard has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 3,814 Periogard users. Check the latest studies of Periogard.

What is Weight fluctuation?

Weight fluctuation is found to be associated with 898 drugs and 1,030 conditions by eHealthMe. Check the latest studies of Weight fluctuation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

3,812 people reported to have side effects when taking Periogard.
Among them, 13 people (0.34%) have Weight fluctuation.

Could Periogard cause Weight fluctuation?

Among these 13 people:

What is the gender of people who have Weight fluctuation when taking Periogard? *

female: 100 %
male: 0.0 %

What is the age of people who have Weight fluctuation when taking Periogard? *

What are other drugs people take besides Periogard? *

Ibuprofen: 13 people, 100.00%
Mycophenolate Mofetil: 13 people, 100.00%
Otezla: 13 people, 100.00%
Oxycodone: 13 people, 100.00%
Meloxicam: 13 people, 100.00%
Magnesium: 13 people, 100.00%
Lyrica: 13 people, 100.00%
Prednisolone: 13 people, 100.00%
Humira: 13 people, 100.00%
Glucosamine: 13 people, 100.00%

What are other side effects people have besides Weight fluctuation? *

Memory Loss: 13 people, 100.00%
Sleep Disorder: 13 people, 100.00%
Fever: 13 people, 100.00%
Hair Loss: 13 people, 100.00%
High Blood Cholesterol: 13 people, 100.00%
Drug Ineffective: 13 people, 100.00%
Irritable Bowel Syndrome: 13 people, 100.00%
Depression: 13 people, 100.00%
Duodenal Ulcer Perforation (untreated ulcer can burn through the wall of the stomach): 13 people, 100.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 13 people, 100.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 100.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 13 people, 100.00%
Stress And Anxiety: 7 people, 53.85%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 46.15%
Urticaria (rash of round, red welts on the skin that itch intensely): 4 people, 30.77%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 30.77%
Fever: 4 people, 30.77%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 23.08%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 15.38%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Periogard and have Weight fluctuation?

- Check whether Weight fluctuation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Periogard:

Periogard (3,814 reports)

Browse all side effects of Periogard:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight fluctuation:

Weight fluctuation (898 drugs)

Browse all the conditions that are associated with Weight fluctuation:

Weight fluctuation (1,030 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Periogard) and Periogard (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.