Periostat and Tooth disorder - a phase IV clinical study of FDA data

Summary:

Tooth disorder is reported as a side effect among people who take Periostat (doxycycline hyclate), especially for people who are female, 60+ old, also take Amoxicillin, and have Metastases to bone.

The phase IV clinical study analyzes which people have Tooth disorder when taking Periostat. It is created by eHealthMe based on reports of 263 people who have side effects when taking Periostat from the FDA, and is updated regularly.

What is Periostat?

Periostat has active ingredients of doxycycline hyclate. eHealthMe is studying from 273 Periostat users. Check the latest studies of Periostat.

What is Tooth disorder?

Tooth disorder (tooth disease) is found to be associated with 1,277 drugs and 1,184 conditions by eHealthMe. Check the latest studies of Tooth disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

263 people reported to have side effects when taking Periostat.
Among them, 19 people (7.22%) have Tooth disorder.

Among these 19 people:

What is the gender of people who have Tooth disorder when taking Periostat? *

female: 94.74 %
male: 5.26 %

What is the age of people who have Tooth disorder when taking Periostat? *

What are other drugs people take besides Periostat? *

What are other side effects people have besides Tooth disorder? *

Joint Pain: 18 people, 94.74%
Joint Swelling: 17 people, 89.47%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 17 people, 89.47%
Gingivitis (inflammation of gums): 17 people, 89.47%
Haemangioma Of Liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver): 17 people, 89.47%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 17 people, 89.47%
Head Injury: 17 people, 89.47%
Insomnia (sleeplessness): 17 people, 89.47%
Intervertebral Disc Protrusion (spinal disc protrusion): 17 people, 89.47%
Weakness: 17 people, 89.47%

What are the existing conditions these people have? *

Stress And Anxiety: 17 people, 89.47%
Metastases To Bone (cancer spreads to bone): 17 people, 89.47%
Lung Cancer - Non-Small Cell (lung cancer): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Periostat and have Tooth disorder?

- Check whether Tooth disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Periostat:

Periostat (273 reports)

Tooth disorder treatments and more:

Tooth disorder (31,515 reports)

Browse all side effects of Periostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tooth disorder:

Tooth disorder (1,277 drugs)

Browse all the conditions that are associated with Tooth disorder:

Tooth disorder (1,184 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Periostat) and Periostat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.