Perjeta and Circulatory collapse - a phase IV clinical study of FDA data

Summary:

Circulatory collapse is reported as a side effect among people who take Perjeta (pertuzumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Herceptin, and have Breast cancer.

The phase IV clinical study analyzes which people have Circulatory collapse when taking Perjeta. It is created by eHealthMe based on reports of 13,356 people who have side effects when taking Perjeta from the FDA, and is updated regularly.

What is Perjeta?

Perjeta has active ingredients of pertuzumab. eHealthMe is studying from 13,388 Perjeta users. Check the latest studies of Perjeta.

What is Circulatory collapse?

Circulatory collapse is found to be associated with 1,123 drugs and 1,402 conditions by eHealthMe. Check the latest studies of Circulatory collapse.

On Jul, 07, 2026

13,356 people reported to have side effects when taking Perjeta.
Among them, 17 people (0.13%) have Circulatory collapse.

Could Perjeta cause Circulatory collapse?

Among these 17 people:

How long have people been on Perjeta when they have Circulatory collapse? *

What is the gender of people who have Circulatory collapse when taking Perjeta? *

female: 100 %
male: 0.0 %

What is the age of people who have Circulatory collapse when taking Perjeta? *

What are other drugs people take besides Perjeta? *

Herceptin: 15 people, 88.24%
Dexamethasone: 8 people, 47.06%
Docetaxel: 7 people, 41.18%
Carboplatin: 6 people, 35.29%
Anastrozole: 2 people, 11.76%
Ranitidine Hydrochloride: 2 people, 11.76%
Pantoprazole Sodium: 2 people, 11.76%
Fulvestrant: 1 person, 5.88%
Arimidex: 1 person, 5.88%
Aspirin: 1 person, 5.88%

What are other side effects people have besides Circulatory collapse? *

Diarrhea: 7 people, 41.18%
Tremor (trembling or shaking movements in one or more parts of your body): 6 people, 35.29%
Pulse Absent: 6 people, 35.29%
Death: 4 people, 23.53%
Fatigue (feeling of tiredness): 2 people, 11.76%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 2 people, 11.76%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 1 person, 5.88%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 1 person, 5.88%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 1 person, 5.88%
Chest Pain: 1 person, 5.88%

What are the existing conditions these people have? *

Breast Cancer: 11 people, 64.71%
Breast Cancer Metastatic: 5 people, 29.41%
Chills (felling of cold): 2 people, 11.76%
Sinusitis (inflammation of sinus): 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%
Dyspnea Exertional: 1 person, 5.88%
Dyspnea (difficult or laboured breathing): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Perjeta and have Circulatory collapse?

- Check whether Circulatory collapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Perjeta:

Perjeta (13,388 reports)

Browse all side effects of Perjeta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Circulatory collapse:

Circulatory collapse (1,123 drugs)

Browse all the conditions that are associated with Circulatory collapse:

Circulatory collapse (1,402 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pertuzumab (the active ingredients of Perjeta) and Perjeta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.