Perjeta and Diverticulitis - a phase IV clinical study of FDA data

Summary:

Diverticulitis is reported as a side effect among people who take Perjeta (pertuzumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Herceptin, and have Breast cancer.

The phase IV clinical study analyzes which people have Diverticulitis when taking Perjeta. It is created by eHealthMe based on reports of 13,356 people who have side effects when taking Perjeta from the FDA, and is updated regularly.

What is Perjeta?

Perjeta has active ingredients of pertuzumab. eHealthMe is studying from 13,388 Perjeta users. Check the latest studies of Perjeta.

What is Diverticulitis?

Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall) is found to be associated with 1,364 drugs and 1,360 conditions by eHealthMe. Check the latest studies of Diverticulitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

13,356 people reported to have side effects when taking Perjeta.
Among them, 16 people (0.12%) have Diverticulitis.

Could Perjeta cause Diverticulitis?

Among these 16 people:

How long have people been on Perjeta when they have Diverticulitis? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Diverticulitis when taking Perjeta? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Diverticulitis when taking Perjeta? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 45.45 %
  • 60+: 54.55 %

What are other drugs people take besides Perjeta? *

  1. Herceptin: 10 people, 62.50%
  2. Dexamethasone: 7 people, 43.75%
  3. Taxotere: 6 people, 37.50%
  4. Ondansetron: 5 people, 31.25%
  5. Carboplatin: 5 people, 31.25%
  6. Docetaxel: 4 people, 25.00%
  7. Trazimera: 3 people, 18.75%
  8. Pantoprazole Sodium: 3 people, 18.75%
  9. Zyrtec: 2 people, 12.50%
  10. Calcium: 2 people, 12.50%

What are other side effects people have besides Diverticulitis? *

  1. Diarrhea: 4 people, 25.00%
  2. Nosebleed (bleeding from nose): 3 people, 18.75%
  3. Fatigue (feeling of tiredness): 3 people, 18.75%
  4. Dyspnea (difficult or laboured breathing): 3 people, 18.75%
  5. White Blood Cell Count Decreased: 2 people, 12.50%
  6. Dehydration (dryness resulting from the removal of water): 2 people, 12.50%
  7. Nausea (feeling of having an urge to vomit): 2 people, 12.50%
  8. Fever: 2 people, 12.50%
  9. Sinus Disorder (disease of sinus): 2 people, 12.50%
  10. Depression: 2 people, 12.50%

What are the existing conditions these people have? *

  1. Breast Cancer: 5 people, 31.25%
  2. Breast Cancer Female: 4 people, 25.00%
  3. Essential Hypertension (primary hypertension): 3 people, 18.75%
  4. Bone Neoplasm (tumour of bone): 2 people, 12.50%
  5. Pain In Jaw: 1 person, 6.25%
  6. Nail Infection: 1 person, 6.25%
  7. Meningioma Malignant (cancerous tumour of membranes that cover the brain and spinal cord just inside the skull): 1 person, 6.25%
  8. High Blood Pressure: 1 person, 6.25%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
  10. Ejection Fraction Decreased (systolic heart failure): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Perjeta and have Diverticulitis?

- Check whether Diverticulitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Perjeta:

Diverticulitis treatments and more:

How severe was Diverticulitis and when was it recovered:

Expand to all the drugs that have ingredients of pertuzumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Perjeta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diverticulitis:

Browse all the conditions that are associated with Diverticulitis:


How the study uses the data?

The study uses data from the FDA. It is based on pertuzumab (the active ingredients of Perjeta) and Perjeta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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