Permax and Diarrhea aggravated - a phase IV clinical study of FDA data

Summary:

Diarrhea aggravated is reported as a side effect among people who take Permax (pergolide mesylate), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Sinemet, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Diarrhea aggravated when taking Permax. It is created by eHealthMe based on reports of 1,529 people who have side effects when taking Permax from the FDA, and is updated regularly.

What is Permax?

Permax has active ingredients of pergolide mesylate. eHealthMe is studying from 1,532 Permax users. Check the latest studies of Permax.

What is Diarrhea aggravated?

Diarrhea aggravated is found to be associated with 2,967 drugs and 1,261 conditions by eHealthMe. Check the latest studies of Diarrhea aggravated.



On Jul, 12, 2026

1,529 people reported to have side effects when taking Permax.
Among them, 31 people (2.03%) have Diarrhea aggravated.

Could Permax cause Diarrhea aggravated?

Among these 31 people:

How long have people been on Permax when they have Diarrhea aggravated? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Diarrhea aggravated when taking Permax? *

  • female: 45.16 %
  • male: 54.84 %

What is the age of people who have Diarrhea aggravated when taking Permax? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.57 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 96.43 %

What are other drugs people take besides Permax? *

  1. Sinemet: 17 people, 54.84%
  2. Tasmar: 16 people, 51.61%
  3. Artane: 7 people, 22.58%
  4. Amantadine: 6 people, 19.35%
  5. Provera: 5 people, 16.13%
  6. Ibuprofen: 5 people, 16.13%
  7. Fluvoxamine Maleate: 4 people, 12.90%
  8. Synthroid: 4 people, 12.90%
  9. Proscar: 3 people, 9.68%
  10. Pletal: 3 people, 9.68%

What are other side effects people have besides Diarrhea aggravated? *

  1. Weight Decreased: 7 people, 22.58%
  2. Pleural Effusion (water on the lungs): 5 people, 16.13%
  3. Depressed Level Of Consciousness: 5 people, 16.13%
  4. Flatulence (flatus expelled through the anus): 5 people, 16.13%
  5. Liver Function Tests Nos Abnormal: 5 people, 16.13%
  6. Abdominal Distension: 5 people, 16.13%
  7. Weakness: 4 people, 12.90%
  8. Nausea And Vomiting: 4 people, 12.90%
  9. Malaise (a feeling of general discomfort or uneasiness): 4 people, 12.90%
  10. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 4 people, 12.90%

What are the existing conditions these people have? *

  1. Parkinson's Disease: 4 people, 12.90%
  2. Depression: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Permax and have Diarrhea aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Permax:

Diarrhea aggravated treatments and more:

How severe was Diarrhea aggravated and when was it recovered:

Expand to all the drugs that have ingredients of pergolide mesylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Permax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diarrhea aggravated:

Browse all the conditions that are associated with Diarrhea aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on pergolide mesylate (the active ingredients of Permax) and Permax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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