Phenergan and Bladder prolapse - a phase IV clinical study of FDA data

Summary:

Bladder prolapse is reported as a side effect among people who take Phenergan (promethazine hydrochloride), especially for people who are female, 60+ old, also take Zometa, and have Pain.

The phase IV clinical study analyzes which people have Bladder prolapse when taking Phenergan. It is created by eHealthMe based on reports of 24,254 people who have side effects when taking Phenergan from the FDA, and is updated regularly.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.

What is Bladder prolapse?

Bladder prolapse (bulging of one or more of the pelvic organs into the vagina) is found to be associated with 309 drugs and 374 conditions by eHealthMe. Check the latest studies of Bladder prolapse.

On Jan, 28, 2026

24,254 people reported to have side effects when taking Phenergan.
Among them, 31 people (0.13%) have Bladder prolapse.

Among these 31 people:

What is the gender of people who have Bladder prolapse when taking Phenergan? *

female: 93.55 %
male: 6.45 %

What is the age of people who have Bladder prolapse when taking Phenergan? *

What are other drugs people take besides Phenergan? *

What are other side effects people have besides Bladder prolapse? *

Stress And Anxiety: 21 people, 67.74%
Urinary Tract Infection: 20 people, 64.52%
Osteonecrosis Of Jaw (death of bone of jaw): 19 people, 61.29%
Dyspnea (difficult or laboured breathing): 19 people, 61.29%
Anaemia (lack of blood): 18 people, 58.06%
Metastases To Bone (cancer spreads to bone): 18 people, 58.06%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 18 people, 58.06%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 18 people, 58.06%
Osteoporosis (bones weak and more likely to break): 18 people, 58.06%
Fatigue (feeling of tiredness): 18 people, 58.06%

What are the existing conditions these people have? *

Pain: 11 people, 35.48%
Stress And Anxiety: 10 people, 32.26%
Metastases To Bone (cancer spreads to bone): 9 people, 29.03%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 25.81%
Neuralgia (pain in one or more nerves): 8 people, 25.81%
Muscle Spasms (muscle contraction): 7 people, 22.58%
Oesophageal Ulcer (ulcer of oesophagus): 7 people, 22.58%
Fatigue (feeling of tiredness): 6 people, 19.35%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 19.35%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 19.35%

* Approximation only. Some reports may have incomplete information.

Do you take Phenergan and have Bladder prolapse?

- Check whether Bladder prolapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Phenergan:

Phenergan (25,312 reports)

Browse all side effects of Phenergan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder prolapse:

Bladder prolapse (309 drugs)

Browse all the conditions that are associated with Bladder prolapse:

Bladder prolapse (374 conditions)

Related publications that referenced our studies

Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on promethazine hydrochloride (the active ingredients of Phenergan) and Phenergan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.