Phentermine and Hydrocephalus - a phase IV clinical study of FDA data

Summary:

Hydrocephalus is reported as a side effect among people who take Phentermine (phentermine hydrochloride), especially for people who are female, 40-49 old, also take Ativan, and have Cough.

The phase IV clinical study analyzes which people have Hydrocephalus when taking Phentermine. It is created by eHealthMe based on reports of 15,359 people who have side effects when taking Phentermine from the FDA, and is updated regularly.

What is Phentermine?

Phentermine has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 19,870 Phentermine users. Check the latest studies of Phentermine.

What is Hydrocephalus?

Hydrocephalus (water on the brain) is found to be associated with 753 drugs and 1,370 conditions by eHealthMe. Check the latest studies of Hydrocephalus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

15,359 people reported to have side effects when taking Phentermine.
Among them, 11 people (0.07%) have Hydrocephalus.

Could Phentermine cause Hydrocephalus?

Among these 11 people:

What is the gender of people who have Hydrocephalus when taking Phentermine? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Hydrocephalus when taking Phentermine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 77.78 %
  • 50-59: 22.22 %
  • 60+: 0.0 %

What are other drugs people take besides Phentermine? *

  1. Synthroid: 4 people, 36.36%
  2. Premarin: 4 people, 36.36%
  3. Effexor: 4 people, 36.36%
  4. Ativan: 4 people, 36.36%
  5. Reglan: 2 people, 18.18%
  6. Provera: 2 people, 18.18%
  7. Ibuprofen: 2 people, 18.18%

What are other side effects people have besides Hydrocephalus? *

  1. Subarachnoid Haemorrhage (blood leaks into the space between two membranes that surround the brain): 7 people, 63.64%
  2. High Blood Pressure: 7 people, 63.64%
  3. Dementia Due To Pick's Disease (madness due to pick's disease): 3 people, 27.27%
  4. Compartment Syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels): 2 people, 18.18%
  5. Headache (pain in head): 2 people, 18.18%
  6. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 18.18%
  7. Photophobia (extreme sensitivity to light): 2 people, 18.18%
  8. Oedema Lower Limb (fluid collection in tissue of lower leg): 2 people, 18.18%
  9. Neck Pain: 2 people, 18.18%
  10. Nausea And Vomiting: 2 people, 18.18%

What are the existing conditions these people have? *

  1. Weight Decreased: 3 people, 27.27%
  2. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 27.27%
  3. Cough: 3 people, 27.27%
  4. Viral Upper Respiratory Tract Infection: 1 person, 9.09%
  5. Nasopharyngitis (inflammation of the nasopharynx): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Phentermine and have Hydrocephalus?

- Check whether Hydrocephalus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Phentermine:

Hydrocephalus treatments and more:

How severe was Hydrocephalus and when was it recovered:

Expand to all the drugs that have ingredients of phentermine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Phentermine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hydrocephalus:

Browse all the conditions that are associated with Hydrocephalus:


How the study uses the data?

The study uses data from the FDA. It is based on phentermine hydrochloride (the active ingredients of Phentermine) and Phentermine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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