Phenylephrine hydrochloride and Pruritus aggravated - a phase IV clinical study of FDA data

Summary:

Pruritus aggravated is reported as a side effect among people who take Phenylephrine hydrochloride (phenylephrine hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Leflunomide, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Pruritus aggravated when taking Phenylephrine hydrochloride. It is created by eHealthMe based on reports of 1,208 people who have side effects when taking Phenylephrine hydrochloride from the FDA, and is updated regularly.

What is Phenylephrine hydrochloride?

Phenylephrine hydrochloride has active ingredients of phenylephrine hydrochloride. eHealthMe is studying from 1,240 Phenylephrine hydrochloride users. Check the latest studies of Phenylephrine hydrochloride.

What is Pruritus aggravated?

Pruritus aggravated (serious severe itching of the skin) is found to be associated with 2,483 drugs and 1,070 conditions by eHealthMe. Check the latest studies of Pruritus aggravated.

On Aug, 04, 2026

1,208 people reported to have side effects when taking Phenylephrine hydrochloride.
Among them, 161 people (13.33%) have Pruritus aggravated.

Could Phenylephrine hydrochloride cause Pruritus aggravated?

Among these 161 people:

How long have people been on Phenylephrine hydrochloride when they have Pruritus aggravated? *

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What is the gender of people who have Pruritus aggravated when taking Phenylephrine hydrochloride? *

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What is the age of people who have Pruritus aggravated when taking Phenylephrine hydrochloride? *

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* Approximation only. Some reports may have incomplete information.

Do you take Phenylephrine hydrochloride and have Pruritus aggravated?

- Check whether Pruritus aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Phenylephrine hydrochloride:

Phenylephrine hydrochloride (1,240 reports)

Pruritus aggravated treatments and more:

Pruritus aggravated (20 reports)

How severe was Pruritus aggravated and when was it recovered:

Pruritus aggravated in Phenylephrine hydrochloride

Expand to all the drugs that have ingredients of phenylephrine hydrochloride:

Pruritus aggravated and drugs with ingredients of phenylephrine hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Phenylephrine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pruritus aggravated:

Pruritus aggravated (2,483 drugs)

Browse all the conditions that are associated with Pruritus aggravated:

Pruritus aggravated (1,070 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on phenylephrine hydrochloride (the active ingredients of Phenylephrine hydrochloride) and Phenylephrine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.