Phenytoin sodium and Partial seizures - a phase IV clinical study of FDA data

Summary:

Partial seizures is reported as a side effect among people who take Phenytoin sodium (phenytoin sodium), especially for people who are male, 50-59 old, have been taking the drug for 10+ years also take Zolpidem, and have Status epilepticus.

The phase IV clinical study analyzes which people have Partial seizures when taking Phenytoin sodium. It is created by eHealthMe based on reports of 6,740 people who have side effects when taking Phenytoin sodium from the FDA, and is updated regularly.

What is Phenytoin sodium?

Phenytoin sodium has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 6,886 Phenytoin sodium users. Check the latest studies of Phenytoin sodium.

What is Partial seizures?

Partial seizures (seizures which affect only a part of the brain at onset) is found to be associated with 478 drugs and 726 conditions by eHealthMe. Check the latest studies of Partial seizures.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

6,740 people reported to have side effects when taking Phenytoin sodium.
Among them, 32 people (0.47%) have Partial seizures.

Could Phenytoin sodium cause Partial seizures?

Among these 32 people:

How long have people been on Phenytoin sodium when they have Partial seizures? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

What is the gender of people who have Partial seizures when taking Phenytoin sodium? *

  • female: 44.44 %
  • male: 55.56 %

What is the age of people who have Partial seizures when taking Phenytoin sodium? *

  • 0-1: 4.17 %
  • 2-9: 4.17 %
  • 10-19: 0.0 %
  • 20-29: 4.17 %
  • 30-39: 25.0 %
  • 40-49: 12.5 %
  • 50-59: 29.17 %
  • 60+: 20.83 %

What are other drugs people take besides Phenytoin sodium? *

  1. Rabeprazole Sodium: 5 people, 15.62%
  2. Seroquel: 5 people, 15.62%
  3. Paxil: 5 people, 15.62%
  4. Gilenya: 5 people, 15.62%
  5. Zolpidem: 5 people, 15.62%
  6. Levetiracetam: 4 people, 12.50%
  7. Keppra: 4 people, 12.50%
  8. Primaxin: 3 people, 9.38%
  9. Valproate Sodium: 3 people, 9.38%
  10. Topiramate: 3 people, 9.38%

What are other side effects people have besides Partial seizures? *

  1. Urinary Tract Infection: 7 people, 21.88%
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 21.88%
  3. Fever: 6 people, 18.75%
  4. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 6 people, 18.75%
  5. White Blood Cell Count Increased: 5 people, 15.62%
  6. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 5 people, 15.62%
  7. Altered State Of Consciousness (altered state of mind): 5 people, 15.62%
  8. Bacterial Infection: 5 people, 15.62%
  9. C-Reactive Protein Increased: 5 people, 15.62%
  10. Convulsions Local (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly in one of the body parts): 5 people, 15.62%

What are the existing conditions these people have? *

  1. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 10 people, 31.25%
  2. Depression: 6 people, 18.75%
  3. Back Pain: 5 people, 15.62%
  4. Gastric Hypomotility (less movement of stomach): 5 people, 15.62%
  5. Sleep Disorder: 5 people, 15.62%
  6. Constipation: 5 people, 15.62%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 15.62%
  8. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 5 people, 15.62%
  9. Gastric Ph Decreased: 5 people, 15.62%
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Phenytoin sodium and have Partial seizures?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Phenytoin sodium:

Partial seizures treatments and more:

How severe was Partial seizures and when was it recovered:

Expand to all the drugs that have ingredients of phenytoin sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Phenytoin sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Partial seizures:

Browse all the conditions that are associated with Partial seizures:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on phenytoin sodium (the active ingredients of Phenytoin sodium) and Phenytoin sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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