Phenytoin and Immunodeficiency disorders - a phase IV clinical study of FDA data

Summary:

Immunodeficiency disorders is reported as a side effect among people who take Phenytoin (phenytoin), especially for people who are female, 30-39 old, also take Folic Acid, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Immunodeficiency disorders when taking Phenytoin. It is created by eHealthMe based on reports of 15,464 people who have side effects when taking Phenytoin from the FDA, and is updated regularly.

What is Phenytoin?

Phenytoin has active ingredients of phenytoin. It is often used in epilepsy. eHealthMe is studying from 15,753 Phenytoin users. Check the latest studies of Phenytoin.

What is Immunodeficiency disorders?

Immunodeficiency disorders is found to be associated with 705 drugs and 942 conditions by eHealthMe. Check the latest studies of Immunodeficiency disorders.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

15,464 people reported to have side effects when taking Phenytoin.
Among them, 26 people (0.17%) have Immunodeficiency disorders.

Could Phenytoin cause Immunodeficiency disorders?

Among these 26 people:

What is the gender of people who have Immunodeficiency disorders when taking Phenytoin? *

female: 68 %
male: 32 %

What is the age of people who have Immunodeficiency disorders when taking Phenytoin? *

What are other drugs people take besides Phenytoin? *

What are other side effects people have besides Immunodeficiency disorders? *

Oedema Peripheral (superficial swelling): 22 people, 84.62%
Otitis (ear infection): 20 people, 76.92%
Chills (felling of cold): 19 people, 73.08%
Fall: 18 people, 69.23%
Intervertebral Disc Protrusion (spinal disc protrusion): 18 people, 69.23%
Fatigue (feeling of tiredness): 18 people, 69.23%
Nasopharyngitis (inflammation of the nasopharynx): 17 people, 65.38%
Muscle Strain (an injury to a muscle in which the muscle fibres tear): 16 people, 61.54%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 16 people, 61.54%
Insomnia (sleeplessness): 16 people, 61.54%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 16 people, 61.54%
Neuralgia (pain in one or more nerves): 13 people, 50.00%
Multiple Myeloma (cancer of the plasma cells): 8 people, 30.77%
Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 3.85%
Streptococcal Infection: 1 person, 3.85%
Rashes (redness): 1 person, 3.85%
Multiple Allergies (allergy to multiple agents): 1 person, 3.85%
Meningitis Bacterial (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 1 person, 3.85%
Food Allergy: 1 person, 3.85%
Eye Infection: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Phenytoin and have Immunodeficiency disorders?

- Check whether Immunodeficiency disorders is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Phenytoin:

Phenytoin (15,753 reports)

Browse all side effects of Phenytoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Immunodeficiency disorders:

Immunodeficiency disorders (705 drugs)

Browse all the conditions that are associated with Immunodeficiency disorders:

Immunodeficiency disorders (942 conditions)

Related publications that referenced our studies

Wandalkar P, Daswani BR, Pandit PT, Ghongane BB, "A case of Phenytoin toxicity", INTERNATIONAL JOURNAL OF ADVANCES IN PHARMACY, BIOLOGY AND CHEMISTRY, 2014 Jan .
Wandalkar P, Daswani BR, Pandit PT, Ghongane BB, "A case of Phenytoin toxicity", INTERNATIONAL JOURNAL OF ADVANCES IN PHARMACY, BIOLOGY AND CHEMISTRY, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on phenytoin (the active ingredients of Phenytoin) and Phenytoin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.