Phesgo and Diarrhea - a phase IV clinical study of FDA data

Summary:

Diarrhea is reported as a side effect among people who take Phesgo (pertuzumab;trastuzumab;hyaluronidase-zzxf), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Paclitaxel, and have Breast cancer.

The phase IV clinical study analyzes which people have Diarrhea when taking Phesgo. It is created by eHealthMe based on reports of 784 people who have side effects when taking Phesgo from the FDA, and is updated regularly.

What is Phesgo?

Phesgo has active ingredients of pertuzumab;trastuzumab;hyaluronidase-zzxf. eHealthMe is studying from 788 Phesgo users. Check the latest studies of Phesgo.

What is Diarrhea?

Diarrhea is found to be associated with 3,727 drugs and 5,753 conditions by eHealthMe. Check the latest studies of Diarrhea.

On Jul, 30, 2026

784 people reported to have side effects when taking Phesgo.
Among them, 71 people (9.06%) have Diarrhea.

Among these 71 people:

How long have people been on Phesgo when they have Diarrhea? *

What is the gender of people who have Diarrhea when taking Phesgo? *

female: 100 %
male: 0.0 %

What is the age of people who have Diarrhea when taking Phesgo? *

What are other drugs people take besides Phesgo? *

What are other side effects people have besides Diarrhea? *

Fatigue (feeling of tiredness): 14 people, 19.72%
Colitis (inflammation of colon): 11 people, 15.49%
Rectal Haemorrhage (bleeding from anus): 11 people, 15.49%
Fever: 9 people, 12.68%
Nausea (feeling of having an urge to vomit): 7 people, 9.86%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 7 people, 9.86%
Rashes (redness): 7 people, 9.86%
High Blood Pressure: 7 people, 9.86%
Nausea And Vomiting: 6 people, 8.45%
Weakness: 6 people, 8.45%

What are the existing conditions these people have? *

Breast Cancer: 42 people, 59.15%
Breast Cancer Metastatic: 10 people, 14.08%
Pain: 6 people, 8.45%
Nausea (feeling of having an urge to vomit): 6 people, 8.45%
Sinusitis (inflammation of sinus): 4 people, 5.63%
High Blood Pressure: 4 people, 5.63%
Metabolic Syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease): 2 people, 2.82%
Iron Deficiency: 2 people, 2.82%
Dyspnea (difficult or laboured breathing): 2 people, 2.82%
Breast Cancer Stage Iv: 2 people, 2.82%

* Approximation only. Some reports may have incomplete information.

Do you take Phesgo and have Diarrhea?

- Check whether Diarrhea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Phesgo:

Phesgo (788 reports)

Diarrhea treatments and more:

Diarrhea (756,290 reports)

How severe was Diarrhea and when was it recovered:

Diarrhea in Phesgo

Expand to all the drugs that have ingredients of pertuzumab;trastuzumab;hyaluronidase-zzxf:

Diarrhea and drugs with ingredients of pertuzumab;trastuzumab;hyaluronidase-zzxf (19 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Phesgo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diarrhea:

Diarrhea (3,727 drugs)

Browse all the conditions that are associated with Diarrhea:

Diarrhea (5,753 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pertuzumab;trastuzumab;hyaluronidase-zzxf (the active ingredients of Phesgo) and Phesgo (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.