Photofrin and Pleural effusion - a phase IV clinical study of FDA data

Summary:

Pleural effusion is reported as a side effect among people who take Photofrin (porfimer sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Carboplatin, and have Pleural mesothelioma malignant.

The phase IV clinical study analyzes which people have Pleural effusion when taking Photofrin. It is created by eHealthMe based on reports of 388 people who have side effects when taking Photofrin from the FDA, and is updated regularly.

What is Photofrin?

Photofrin has active ingredients of porfimer sodium. eHealthMe is studying from 388 Photofrin users. Check the latest studies of Photofrin.

What is Pleural effusion?

Pleural effusion (water on the lungs) is found to be associated with 2,221 drugs and 3,149 conditions by eHealthMe. Check the latest studies of Pleural effusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

388 people reported to have side effects when taking Photofrin.
Among them, 12 people (3.09%) have Pleural effusion.

Among these 12 people:

How long have people been on Photofrin when they have Pleural effusion? *

What is the gender of people who have Pleural effusion when taking Photofrin? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Pleural effusion when taking Photofrin? *

What are other drugs people take besides Photofrin? *

What are other side effects people have besides Pleural effusion? *

Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 50.00%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 5 people, 41.67%
Pneumonia: 5 people, 41.67%
Hypotension (abnormally low blood pressure): 5 people, 41.67%
Localised Oedema (fluid retention in a particular part of the body): 4 people, 33.33%
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 4 people, 33.33%
Empyema (collection of pus in a cavity in the body): 4 people, 33.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 33.33%
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 4 people, 33.33%
Pulmonary Air Leakage: 4 people, 33.33%

What are the existing conditions these people have? *

Pleural Mesothelioma Malignant (cancer of the pleura, or the membrane that lines the lungs): 4 people, 33.33%
Oesophageal Carcinoma (cancer tumour of oesophagus): 3 people, 25.00%
Non-Small Cell Lung Cancer Stage Ii: 2 people, 16.67%
Metastases To Peritoneum (cancer spreads to peritoneum): 1 person, 8.33%
Malignant Peritoneal Neoplasm (cancer tumour of peritoneum): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Photofrin and have Pleural effusion?

- Check whether Pleural effusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Photofrin:

Photofrin (388 reports)

Pleural effusion treatments and more:

Pleural effusion (84,634 reports)

Browse all side effects of Photofrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pleural effusion:

Pleural effusion (2,221 drugs)

Browse all the conditions that are associated with Pleural effusion:

Pleural effusion (3,149 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on porfimer sodium (the active ingredients of Photofrin) and Photofrin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.