Phytonadione and Gallstones - a phase IV clinical study of FDA data

Summary:

Gallstones is reported as a side effect among people who take Phytonadione (phytonadione), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Vancomycin, and have Pulmonary hypertension.

The phase IV clinical study analyzes which people have Gallstones when taking Phytonadione. It is created by eHealthMe based on reports of 2,865 people who have side effects when taking Phytonadione from the FDA, and is updated regularly.

What is Phytonadione?

Phytonadione has active ingredients of phytonadione. It is often used in hemorrhagic stroke. eHealthMe is studying from 2,870 Phytonadione users. Check the latest studies of Phytonadione.

What is Gallstones?

Gallstones (stone formation by bile component) is found to be associated with 1,804 drugs and 2,100 conditions by eHealthMe. Check the latest studies of Gallstones.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

2,865 people reported to have side effects when taking Phytonadione.
Among them, 26 people (0.91%) have Gallstones.

Could Phytonadione cause Gallstones?

Among these 26 people:

How long have people been on Phytonadione when they have Gallstones? *

  • < 1 month: 85.71 %
  • 1 - 6 months: 14.29 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Gallstones when taking Phytonadione? *

  • female: 84.62 %
  • male: 15.38 %

What is the age of people who have Gallstones when taking Phytonadione? *

  • 0-1: 11.54 %
  • 2-9: 7.69 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.85 %
  • 40-49: 34.62 %
  • 50-59: 23.08 %
  • 60+: 19.23 %

What are other drugs people take besides Phytonadione? *

  1. Vancomycin: 10 people, 38.46%
  2. Protonix: 8 people, 30.77%
  3. Aldactone: 8 people, 30.77%
  4. Zofran: 8 people, 30.77%
  5. Flolan: 8 people, 30.77%
  6. Lasix: 7 people, 26.92%
  7. Lactulose: 6 people, 23.08%
  8. Tracleer: 5 people, 19.23%
  9. Zoloft: 5 people, 19.23%
  10. Coumadin: 5 people, 19.23%

What are other side effects people have besides Gallstones? *

  1. Ascites (accumulation of fluid in the abdominal cavity): 10 people, 38.46%
  2. Hepatotoxicity (chemical-driven liver damage): 9 people, 34.62%
  3. Fever: 9 people, 34.62%
  4. Nausea And Vomiting: 8 people, 30.77%
  5. Thrombocytopenia (decrease of platelets in blood): 8 people, 30.77%
  6. Fatigue (feeling of tiredness): 8 people, 30.77%
  7. Alanine Aminotransferase Increased: 8 people, 30.77%
  8. Aspartate Aminotransferase Increased: 8 people, 30.77%
  9. Abdominal Distension: 7 people, 26.92%
  10. Bleeding Disorders: 7 people, 26.92%

What are the existing conditions these people have? *

  1. Pulmonary Hypertension (increase in blood pressure in the lung artery): 8 people, 30.77%
  2. Pneumonia: 4 people, 15.38%
  3. Multiple Myeloma (cancer of the plasma cells): 3 people, 11.54%
  4. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 11.54%
  5. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 3 people, 11.54%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.54%
  7. Headache (pain in head): 3 people, 11.54%
  8. Muscle Spasms (muscle contraction): 3 people, 11.54%
  9. Urination - Excessive Volume: 2 people, 7.69%
  10. Cardiac Disorder: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Phytonadione and have Gallstones?

- Check whether Gallstones is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Phytonadione:

Gallstones treatments and more:

How severe was Gallstones and when was it recovered:

Expand to all the drugs that have ingredients of phytonadione:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Phytonadione:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallstones:

Browse all the conditions that are associated with Gallstones:


How the study uses the data?

The study uses data from the FDA. It is based on phytonadione (the active ingredients of Phytonadione) and Phytonadione (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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