Pioglitazone and Bone pain - a phase IV clinical study of FDA data

Summary:

Bone pain is reported as a side effect among people who take Pioglitazone (pioglitazone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Glipizide, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Bone pain when taking Pioglitazone. It is created by eHealthMe based on reports of 12,725 people who have side effects when taking Pioglitazone from the FDA, and is updated regularly.

What is Pioglitazone?

Pioglitazone has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 12,864 Pioglitazone users. Check the latest studies of Pioglitazone.

What is Bone pain?

Bone pain is found to be associated with 1,812 drugs and 1,777 conditions by eHealthMe. Check the latest studies of Bone pain.

On Jul, 12, 2026

12,725 people reported to have side effects when taking Pioglitazone.
Among them, 44 people (0.35%) have Bone pain.

Among these 44 people:

How long have people been on Pioglitazone when they have Bone pain? *

What is the gender of people who have Bone pain when taking Pioglitazone? *

female: 32.56 %
male: 67.44 %

What is the age of people who have Bone pain when taking Pioglitazone? *

What are other drugs people take besides Pioglitazone? *

What are other side effects people have besides Bone pain? *

Weakness: 28 people, 63.64%
Pain: 27 people, 61.36%
Stress And Anxiety: 26 people, 59.09%
Constipation: 19 people, 43.18%
Pleural Effusion (water on the lungs): 18 people, 40.91%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 18 people, 40.91%
Kidney Stones: 18 people, 40.91%
Discomfort: 18 people, 40.91%
Deformity (disfigurement): 17 people, 38.64%
Emotional Distress: 17 people, 38.64%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 22.73%
Neoplasm Malignant (cancer tumour): 9 people, 20.45%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 4.55%
Blood Pressure Abnormal: 1 person, 2.27%
Depression: 1 person, 2.27%
Hair Loss: 1 person, 2.27%
Hyperglycemia (high blood sugar): 1 person, 2.27%
Indigestion: 1 person, 2.27%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 2.27%
Lymphoma (cancer that begins in immune system cells): 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Pioglitazone and have Bone pain?

- Check whether Bone pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pioglitazone:

Pioglitazone (12,864 reports)

Bone pain treatments and more:

Bone pain (76,561 reports)

Browse all side effects of Pioglitazone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone pain:

Bone pain (1,812 drugs)

Browse all the conditions that are associated with Bone pain:

Bone pain (1,777 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pioglitazone hydrochloride (the active ingredients of Pioglitazone) and Pioglitazone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.