Pioglitazone and Dehydration - a phase IV clinical study of FDA data

Summary:

Dehydration is reported as a side effect among people who take Pioglitazone (pioglitazone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Metformin, and have High blood pressure.

The phase IV clinical study analyzes which people have Dehydration when taking Pioglitazone. It is created by eHealthMe based on reports of 12,725 people who have side effects when taking Pioglitazone from the FDA, and is updated regularly.

What is Pioglitazone?

Pioglitazone has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 12,864 Pioglitazone users. Check the latest studies of Pioglitazone.

What is Dehydration?

Dehydration (dryness resulting from the removal of water) is found to be associated with 2,753 drugs and 3,350 conditions by eHealthMe. Check the latest studies of Dehydration.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

12,725 people reported to have side effects when taking Pioglitazone.
Among them, 249 people (1.96%) have Dehydration.

Among these 249 people:

* Approximation only. Some reports may have incomplete information.

Do you take Pioglitazone and have Dehydration?

- Check whether Dehydration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pioglitazone:

Pioglitazone (12,864 reports)

Dehydration treatments and more:

Dehydration (173,274 reports)

How severe was Dehydration and when was it recovered:

Dehydration in Pioglitazone

Expand to all the drugs that have ingredients of pioglitazone hydrochloride:

Dehydration and drugs with ingredients of pioglitazone hydrochloride (915 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pioglitazone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dehydration:

Dehydration (2,753 drugs)

Browse all the conditions that are associated with Dehydration:

Dehydration (3,350 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pioglitazone hydrochloride (the active ingredients of Pioglitazone) and Pioglitazone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.