Pioglitazone and Lip swelling - a phase IV clinical study of FDA data

Summary:

Lip swelling is reported as a side effect among people who take Pioglitazone (pioglitazone hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Amlodipine, and have High blood pressure.

The phase IV clinical study analyzes which people have Lip swelling when taking Pioglitazone. It is created by eHealthMe based on reports of 12,725 people who have side effects when taking Pioglitazone from the FDA, and is updated regularly.

What is Pioglitazone?

Pioglitazone has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 12,864 Pioglitazone users. Check the latest studies of Pioglitazone.

What is Lip swelling?

Lip swelling is found to be associated with 1,250 drugs and 1,581 conditions by eHealthMe. Check the latest studies of Lip swelling.

On Jul, 19, 2026

12,725 people reported to have side effects when taking Pioglitazone.
Among them, 26 people (0.2%) have Lip swelling.

Among these 26 people:

How long have people been on Pioglitazone when they have Lip swelling? *

What is the gender of people who have Lip swelling when taking Pioglitazone? *

female: 42.31 %
male: 57.69 %

What is the age of people who have Lip swelling when taking Pioglitazone? *

What are other drugs people take besides Pioglitazone? *

What are other side effects people have besides Lip swelling? *

Weakness: 8 people, 30.77%
Dizziness: 8 people, 30.77%
Eye Swelling: 7 people, 26.92%
Swelling Face: 7 people, 26.92%
Fatigue (feeling of tiredness): 7 people, 26.92%
Headache (pain in head): 5 people, 19.23%
Arrhythmias (irregular heartbeat): 5 people, 19.23%
Oedema Peripheral (superficial swelling): 5 people, 19.23%
Femoral Artery Occlusion (obstruction in artery of femur): 4 people, 15.38%
Hypertensive Heart Disease: 4 people, 15.38%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 19.23%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
High Blood Cholesterol: 2 people, 7.69%
Urinary Tract Infection: 1 person, 3.85%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 3.85%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 3.85%
Bipolar Disorder (mood disorder): 1 person, 3.85%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 3.85%
Dry Eyes (lack of adequate tears): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Pioglitazone and have Lip swelling?

- Check whether Lip swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pioglitazone:

Pioglitazone (12,864 reports)

Lip swelling treatments and more:

Lip swelling (33,385 reports)

Browse all side effects of Pioglitazone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lip swelling:

Lip swelling (1,250 drugs)

Browse all the conditions that are associated with Lip swelling:

Lip swelling (1,581 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pioglitazone hydrochloride (the active ingredients of Pioglitazone) and Pioglitazone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.