Piroxicam and Mental status changes - a phase IV clinical study of FDA data

Summary:

Mental status changes is reported as a side effect among people who take Piroxicam (piroxicam), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Hydrochlorothiazide, and have High blood pressure.

The phase IV clinical study analyzes which people have Mental status changes when taking Piroxicam. It is created by eHealthMe based on reports of 8,414 people who have side effects when taking Piroxicam from the FDA, and is updated regularly.

What is Piroxicam?

Piroxicam has active ingredients of piroxicam. It is often used in arthritis. eHealthMe is studying from 8,582 Piroxicam users. Check the latest studies of Piroxicam.

What is Mental status changes?

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation) is found to be associated with 1,496 drugs and 1,760 conditions by eHealthMe. Check the latest studies of Mental status changes.

On Jul, 29, 2026

8,414 people reported to have side effects when taking Piroxicam.
Among them, 44 people (0.52%) have Mental status changes.

Could Piroxicam cause Mental status changes?

Among these 44 people:

How long have people been on Piroxicam when they have Mental status changes? *

What is the gender of people who have Mental status changes when taking Piroxicam? *

female: 31.82 %
male: 68.18 %

What is the age of people who have Mental status changes when taking Piroxicam? *

What are other drugs people take besides Piroxicam? *

What are other side effects people have besides Mental status changes? *

Fatigue (feeling of tiredness): 33 people, 75.00%
Depression: 30 people, 68.18%
Dyspnea (difficult or laboured breathing): 29 people, 65.91%
Chest Pain: 29 people, 65.91%
Exostosis (formation of new bone on the surface of a bone): 28 people, 63.64%
Thrombocytopenia (decrease of platelets in blood): 27 people, 61.36%
Constipation: 27 people, 61.36%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 27 people, 61.36%
Aortic Valve Incompetence: 27 people, 61.36%
Joint Pain: 27 people, 61.36%

What are the existing conditions these people have? *

High Blood Pressure: 29 people, 65.91%
Joint Pain: 27 people, 61.36%
Multiple Myeloma (cancer of the plasma cells): 26 people, 59.09%
Diarrhea: 25 people, 56.82%
Fluid Retention (an abnormal accumulation of fluid in the blood): 25 people, 56.82%
Mood Swings (an extreme or rapid change in mood): 25 people, 56.82%
High Blood Cholesterol: 25 people, 56.82%
Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 25 people, 56.82%
Seasonal Allergy (allergic condition due to certain season): 18 people, 40.91%
Blood Triglycerides Decreased: 18 people, 40.91%

* Approximation only. Some reports may have incomplete information.

Do you take Piroxicam and have Mental status changes?

- Check whether Mental status changes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Piroxicam:

Piroxicam (8,582 reports)

Browse all side effects of Piroxicam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mental status changes:

Mental status changes (1,496 drugs)

Browse all the conditions that are associated with Mental status changes:

Mental status changes (1,760 conditions)

Related publications that referenced our studies

Kola E, Bakalli I, Celaj E, Lluka R, Heta S, Sallabanda S, "Stomach perforation from piroxicam poisoning", Paediatrics Today, 2012 Jun .
Kola E, Bakalli I, Celaj E, Lluka R, Heta S, Sallabanda S, "Stomach perforation from piroxicam poisoning", Paediatrics Today, 2012 Jun .

How the study uses the data?

The study uses data from the FDA. It is based on piroxicam (the active ingredients of Piroxicam) and Piroxicam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.