Pl and Cardiac failure - a phase IV clinical study of FDA data

Summary:

Cardiac failure is reported as a side effect among people who take Pl (polypodium leucotomos), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Buscopan, and have High blood pressure.

The phase IV clinical study analyzes which people have Cardiac failure when taking Pl. It is created by eHealthMe based on reports of 640 people who have side effects when taking Pl from the FDA, and is updated regularly.

What is Pl?

Pl has active ingredients of polypodium leucotomos. eHealthMe is studying from 640 Pl users. Check the latest studies of Pl.

What is Cardiac failure?

Cardiac failure is found to be associated with 2,056 drugs and 2,210 conditions by eHealthMe. Check the latest studies of Cardiac failure.

On Jul, 22, 2026

640 people reported to have side effects when taking Pl.
Among them, 23 people (3.59%) have Cardiac failure.

Among these 23 people:

How long have people been on Pl when they have Cardiac failure? *

What is the gender of people who have Cardiac failure when taking Pl? *

female: 47.83 %
male: 52.17 %

What is the age of people who have Cardiac failure when taking Pl? *

What are other drugs people take besides Pl? *

What are other side effects people have besides Cardiac failure? *

Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 5 people, 21.74%
Hyperkalemia (damage to or disease of the kidney): 5 people, 21.74%
Urinary Tract Infection: 5 people, 21.74%
Thrombocytopenia (decrease of platelets in blood): 5 people, 21.74%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 5 people, 21.74%
Systemic Candida (whole body fungal infection): 5 people, 21.74%
Renal Impairment (severely reduced kidney function): 4 people, 17.39%
Constipation: 4 people, 17.39%
Autoimmune Myocarditis (inflammation of the heart muscle by immune system disorder): 4 people, 17.39%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 13.04%

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 30.43%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 26.09%
Lung Cancer - Non-Small Cell (lung cancer): 5 people, 21.74%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 17.39%
Osteoporosis (bones weak and more likely to break): 4 people, 17.39%
Breast Cancer: 3 people, 13.04%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 13.04%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 13.04%
Type 2 Diabetes: 3 people, 13.04%
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Pl and have Cardiac failure?

- Check whether Cardiac failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pl:

Pl (640 reports)

Cardiac failure treatments and more:

Cardiac failure (147,157 reports)

Browse all side effects of Pl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac failure:

Cardiac failure (2,056 drugs)

Browse all the conditions that are associated with Cardiac failure:

Cardiac failure (2,210 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on polypodium leucotomos (the active ingredients of Pl) and Pl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.