Plaquenil and Neck deformity - a phase IV clinical study of FDA data

Summary:

Neck deformity is reported as a side effect among people who take Plaquenil (hydroxychloroquine sulfate), especially for people who are female, 40-49 old, have been taking the drug for 10+ years also take Xeljanz, and have Psoriasis.

The phase IV clinical study analyzes which people have Neck deformity when taking Plaquenil. It is created by eHealthMe based on reports of 88,348 people who have side effects when taking Plaquenil from the FDA, and is updated regularly.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,019 Plaquenil users. Check the latest studies of Plaquenil.

What is Neck deformity?

Neck deformity (neck malformation) is found to be associated with 88 drugs and 125 conditions by eHealthMe. Check the latest studies of Neck deformity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

88,348 people reported to have side effects when taking Plaquenil.
Among them, 87 people (0.1%) have Neck deformity.

Among these 87 people:

How long have people been on Plaquenil when they have Neck deformity? *

What is the gender of people who have Neck deformity when taking Plaquenil? *

female: 93.02 %
male: 6.98 %

What is the age of people who have Neck deformity when taking Plaquenil? *

What are other drugs people take besides Plaquenil? *

What are other side effects people have besides Neck deformity? *

Drug Ineffective: 84 people, 96.55%
Pain: 81 people, 93.10%
Joint Pain: 79 people, 90.80%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 78 people, 89.66%
Joint Swelling: 78 people, 89.66%
Joint Stiffness: 76 people, 87.36%
Mood Swings (an extreme or rapid change in mood): 74 people, 85.06%
Bone Density Abnormal: 74 people, 85.06%
Weakness: 74 people, 85.06%
Neck Mass (mass in neck): 71 people, 81.61%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 4 people, 4.60%
Pain: 3 people, 3.45%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 2.30%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 2.30%
Polyarthritis (arthritis which involves 5 or more joints simultaneously): 2 people, 2.30%
Stress And Anxiety: 1 person, 1.15%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 1.15%
Depression: 1 person, 1.15%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 1.15%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 1.15%

* Approximation only. Some reports may have incomplete information.

Do you take Plaquenil and have Neck deformity?

- Check whether Neck deformity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Plaquenil:

Plaquenil (91,019 reports)

Browse all side effects of Plaquenil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neck deformity:

Neck deformity (88 drugs)

Browse all the conditions that are associated with Neck deformity:

Neck deformity (125 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.