Plaquenil and Osteitis - a phase IV clinical study of FDA data

Summary:

Osteitis is reported as a side effect among people who take Plaquenil (hydroxychloroquine sulfate), especially for people who are female, 50-59 old, also take Methotrexate, and have Osteoporosis.

The phase IV clinical study analyzes which people have Osteitis when taking Plaquenil. It is created by eHealthMe based on reports of 88,348 people who have side effects when taking Plaquenil from the FDA, and is updated regularly.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,018 Plaquenil users. Check the latest studies of Plaquenil.

What is Osteitis?

Osteitis (a general term for inflammation of bone) is found to be associated with 620 drugs and 454 conditions by eHealthMe. Check the latest studies of Osteitis.

On Jul, 18, 2026

88,348 people reported to have side effects when taking Plaquenil.
Among them, 74 people (0.08%) have Osteitis.

Among these 74 people:

What is the gender of people who have Osteitis when taking Plaquenil? *

female: 77.03 %
male: 22.97 %

What is the age of people who have Osteitis when taking Plaquenil? *

What are other drugs people take besides Plaquenil? *

What are other side effects people have besides Osteitis? *

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 52 people, 70.27%
Pain: 51 people, 68.92%
Cellulitis (infection under the skin): 50 people, 67.57%
Bone Disorder: 47 people, 63.51%
Tooth Injury: 47 people, 63.51%
Anaemia (lack of blood): 45 people, 60.81%
Bone Pain: 45 people, 60.81%
Oedema Peripheral (superficial swelling): 44 people, 59.46%
Osteoporosis (bones weak and more likely to break): 43 people, 58.11%
Spinal Osteoarthritis (joint cartilage loss in spine): 42 people, 56.76%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 49 people, 66.22%
Thrombocytopenia (decrease of platelets in blood): 11 people, 14.86%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 6.76%
Inflammation: 5 people, 6.76%
Multiple Myeloma (cancer of the plasma cells): 2 people, 2.70%
Seasonal Allergy (allergic condition due to certain season): 1 person, 1.35%
Pain: 1 person, 1.35%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 1.35%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 1.35%
Acne (skin problems that cause pimples): 1 person, 1.35%

* Approximation only. Some reports may have incomplete information.

Do you take Plaquenil and have Osteitis?

- Check whether Osteitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Plaquenil:

Plaquenil (91,018 reports)

Osteitis treatments and more:

Osteitis (5,726 reports)

Browse all side effects of Plaquenil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteitis:

Osteitis (620 drugs)

Browse all the conditions that are associated with Osteitis:

Osteitis (454 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.