Plaquenil and Sternal fracture - a phase IV clinical study of FDA data

Summary:

Sternal fracture is reported as a side effect among people who take Plaquenil (hydroxychloroquine sulfate), especially for people who are female, 60+ old, also take Remicade, and have Osteoporosis.

The phase IV clinical study analyzes which people have Sternal fracture when taking Plaquenil. It is created by eHealthMe based on reports of 88,348 people who have side effects when taking Plaquenil from the FDA, and is updated regularly.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,019 Plaquenil users. Check the latest studies of Plaquenil.

What is Sternal fracture?

Sternal fracture is found to be associated with 243 drugs and 257 conditions by eHealthMe. Check the latest studies of Sternal fracture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

88,348 people reported to have side effects when taking Plaquenil.
Among them, 14 people (0.02%) have Sternal fracture.

$Could Plaquenil cause Sternal fracture?$

Among these 14 people:

What is the gender of people who have Sternal fracture when taking Plaquenil? *

female: 76.92 %
male: 23.08 %

What is the age of people who have Sternal fracture when taking Plaquenil? *

What are other drugs people take besides Plaquenil? *

What are other side effects people have besides Sternal fracture? *

Fall: 8 people, 57.14%
Drug Ineffective: 8 people, 57.14%
Road Traffic Accident: 7 people, 50.00%
Pneumonia: 6 people, 42.86%
Rib Fracture: 6 people, 42.86%
Diarrhea: 5 people, 35.71%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 35.71%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 35.71%
Femur Fracture: 4 people, 28.57%
Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 4 people, 28.57%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 4 people, 28.57%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 21.43%
Oesophageal Disorder (disease of oesophagus): 1 person, 7.14%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Plaquenil and have Sternal fracture?

- Check whether Sternal fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Plaquenil:

Plaquenil (91,019 reports)

Browse all side effects of Plaquenil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sternal fracture:

Sternal fracture (243 drugs)

Browse all the conditions that are associated with Sternal fracture:

Sternal fracture (257 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.