Plaquenil and Vasodilatation - a phase IV clinical study of FDA data

Summary:

Vasodilatation is reported as a side effect among people who take Plaquenil (hydroxychloroquine sulfate), especially for people who are female, 40-49 old, also take Actemra, and have Juvenile rheumatoid arthritis.

The phase IV clinical study analyzes which people have Vasodilatation when taking Plaquenil. It is created by eHealthMe based on reports of 88,348 people who have side effects when taking Plaquenil from the FDA, and is updated regularly.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,019 Plaquenil users. Check the latest studies of Plaquenil.

What is Vasodilatation?

Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls) is found to be associated with 541 drugs and 550 conditions by eHealthMe. Check the latest studies of Vasodilatation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

88,348 people reported to have side effects when taking Plaquenil.
Among them, 30 people (0.03%) have Vasodilatation.

Among these 30 people:

What is the gender of people who have Vasodilatation when taking Plaquenil? *

female: 60 %
male: 40 %

What is the age of people who have Vasodilatation when taking Plaquenil? *

What are other drugs people take besides Plaquenil? *

What are other side effects people have besides Vasodilatation? *

Drug Ineffective: 17 people, 56.67%
Weight Increased: 14 people, 46.67%
Headache (pain in head): 13 people, 43.33%
Joint Swelling: 13 people, 43.33%
Fatigue (feeling of tiredness): 13 people, 43.33%
Gastritis (inflammation of stomach): 12 people, 40.00%
Joint Pain: 12 people, 40.00%
Gait Disturbance: 12 people, 40.00%
Chest Pain: 12 people, 40.00%
Muscle Spasms (muscle contraction): 12 people, 40.00%

What are the existing conditions these people have? *

Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 9 people, 30.00%
Pericarditis (inflammation of the pericardium): 7 people, 23.33%
Temporal Lobe Epilepsy (a term that refers to a condition where seizures are generated in the portion of the brain called the temporal lobe): 5 people, 16.67%
Osteoporosis (bones weak and more likely to break): 5 people, 16.67%
Ascites (accumulation of fluid in the abdominal cavity): 5 people, 16.67%
Cardiac Failure: 5 people, 16.67%
Diarrhea: 5 people, 16.67%
Gastritis - Chronic (long lasting inflammation of stomach): 5 people, 16.67%
Mixed Connective Tissue Disease (an autoimmune disease, in which the body's defence system attacks itself): 5 people, 16.67%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Plaquenil and have Vasodilatation?

- Check whether Vasodilatation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Plaquenil:

Plaquenil (91,019 reports)

Vasodilatation treatments and more:

Vasodilatation (6,932 reports)

Browse all side effects of Plaquenil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vasodilatation:

Vasodilatation (541 drugs)

Browse all the conditions that are associated with Vasodilatation:

Vasodilatation (550 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.