Plavix and Onychoclasis - a phase IV clinical study of FDA data

Summary:

Onychoclasis is reported as a side effect among people who take Plavix (clopidogrel bisulfate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lisinopril, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Onychoclasis when taking Plavix. It is created by eHealthMe based on reports of 147,094 people who have side effects when taking Plavix from the FDA, and is updated regularly.

What is Plavix?

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. eHealthMe is studying from 151,178 Plavix users. Check the latest studies of Plavix.

What is Onychoclasis?

Onychoclasis (breaking of the nails) is found to be associated with 616 drugs and 607 conditions by eHealthMe. Check the latest studies of Onychoclasis.



On Jul, 10, 2026

147,094 people reported to have side effects when taking Plavix.
Among them, 70 people (0.05%) have Onychoclasis.

Could Plavix cause Onychoclasis?

Among these 70 people:

How long have people been on Plavix when they have Onychoclasis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Onychoclasis when taking Plavix? *

  • female: 71.64 %
  • male: 28.36 %

What is the age of people who have Onychoclasis when taking Plavix? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 42.86 %
  • 60+: 57.14 %

What are other drugs people take besides Plavix? *

  1. Lasix: 25 people, 35.71%
  2. Lisinopril: 25 people, 35.71%
  3. Taxotere: 24 people, 34.29%
  4. Aranesp: 24 people, 34.29%
  5. Aredia: 24 people, 34.29%
  6. Claritin: 24 people, 34.29%
  7. Compazine: 24 people, 34.29%
  8. Dilaudid: 24 people, 34.29%
  9. Glipizide: 24 people, 34.29%
  10. Morphine: 24 people, 34.29%

What are other side effects people have besides Onychoclasis? *

  1. Nausea (feeling of having an urge to vomit): 35 people, 50.00%
  2. Abdominal Pain Upper: 34 people, 48.57%
  3. Diarrhea: 33 people, 47.14%
  4. Fungal Nail Infection: 30 people, 42.86%
  5. Fatigue (feeling of tiredness): 30 people, 42.86%
  6. Rashes (redness): 29 people, 41.43%
  7. Head Injury: 29 people, 41.43%
  8. General Physical Health Deterioration (weak health status): 28 people, 40.00%
  9. Stress And Anxiety: 27 people, 38.57%
  10. Chest Pain: 26 people, 37.14%

What are the existing conditions these people have? *

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 15 people, 21.43%
  2. High Blood Pressure: 12 people, 17.14%
  3. Cardiac Disorder: 10 people, 14.29%
  4. Type 2 Diabetes: 9 people, 12.86%
  5. Heart Rate Irregular: 5 people, 7.14%
  6. High Blood Cholesterol: 5 people, 7.14%
  7. Multiple Myeloma (cancer of the plasma cells): 5 people, 7.14%
  8. Prostate Cancer: 4 people, 5.71%
  9. Stress And Anxiety: 3 people, 4.29%
  10. Osteoporosis (bones weak and more likely to break): 2 people, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Plavix and have Onychoclasis?

- Check whether Onychoclasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Plavix:

Onychoclasis treatments and more:

How severe was Onychoclasis and when was it recovered:

Expand to all the drugs that have ingredients of clopidogrel bisulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plavix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Onychoclasis:

Browse all the conditions that are associated with Onychoclasis:


How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel bisulfate (the active ingredients of Plavix) and Plavix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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