Plegridy and Bipolar disorder - a phase IV clinical study of FDA data
Summary:
Bipolar disorder is reported as a side effect among people who take Plegridy (peginterferon beta-1a), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Biotin, and have Multiple sclerosis.
The phase IV clinical study analyzes which people have Bipolar disorder when taking Plegridy. It is created by eHealthMe based on reports of 14,748 people who have side effects when taking Plegridy from the FDA, and is updated regularly.
What is Plegridy?
Plegridy has active ingredients of peginterferon beta-1a. eHealthMe is studying from 14,764 Plegridy users. Check the latest studies of Plegridy.
What is Bipolar disorder?
Bipolar disorder (mood disorder) is found to be associated with 914 drugs and 1,230 conditions by eHealthMe. Check the latest studies of Bipolar disorder.
14,748 people reported to have side effects when taking Plegridy.
Among them, 24 people (0.16%) have Bipolar disorder.

Among these 24 people:
How long have people been on Plegridy when they have Bipolar disorder? *
- < 1 month: 20 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 80 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Bipolar disorder when taking Plegridy? *
- female: 95.83 %
- male: 4.17 %
What is the age of people who have Bipolar disorder when taking Plegridy? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 14.29 %
- 40-49: 0.0 %
- 50-59: 28.57 %
- 60+: 57.14 %
What are other drugs people take besides Plegridy? *
- Ampyra: 8 people, 33.33%
- Vitamin D3: 8 people, 33.33%
- Biotin: 8 people, 33.33%
- Adderall: 7 people, 29.17%
- Echinacea: 7 people, 29.17%
- Effexor Xr: 7 people, 29.17%
- Nexium: 7 people, 29.17%
- Copaxone: 7 people, 29.17%
- Calcium: 7 people, 29.17%
- Celebrex: 7 people, 29.17%
What are other side effects people have besides Bipolar disorder? *
- Fatigue (feeling of tiredness): 14 people, 58.33%
- Drowsiness: 8 people, 33.33%
- Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 29.17%
- Pain In Extremity: 6 people, 25.00%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 6 people, 25.00%
- Gait Disturbance: 6 people, 25.00%
- Feeling Abnormal: 6 people, 25.00%
- Feeling Of Despair: 5 people, 20.83%
- Memory Loss: 5 people, 20.83%
- Hypersensitivity: 5 people, 20.83%
What are the existing conditions these people have? *
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 22 people, 91.67%
- Multiple Allergies (allergy to multiple agents): 2 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Plegridy and have Bipolar disorder?
- Check whether Bipolar disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Plegridy:
- Plegridy (14,764 reports)
Bipolar disorder treatments and more:
- Bipolar disorder (109,428 reports)
How severe was Bipolar disorder and when was it recovered:
Expand to all the drugs that have ingredients of peginterferon beta-1a:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Plegridy:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Bipolar disorder:
- Bipolar disorder (914 drugs)
Browse all the conditions that are associated with Bipolar disorder:
- Bipolar disorder (1,230 conditions)
Related publications that referenced our studies
- Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .
- Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on peginterferon beta-1a (the active ingredients of Plegridy) and Plegridy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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