Plegridy and Burning sensation - a phase IV clinical study of FDA data

Summary:

Burning sensation is reported as a side effect among people who take Plegridy (peginterferon beta-1a), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Ampyra, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Burning sensation when taking Plegridy. It is created by eHealthMe based on reports of 14,748 people who have side effects when taking Plegridy from the FDA, and is updated regularly.

What is Plegridy?

Plegridy has active ingredients of peginterferon beta-1a. eHealthMe is studying from 14,764 Plegridy users. Check the latest studies of Plegridy.

What is Burning sensation?

Burning sensation is found to be associated with 2,016 drugs and 2,077 conditions by eHealthMe. Check the latest studies of Burning sensation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

14,748 people reported to have side effects when taking Plegridy.
Among them, 92 people (0.62%) have Burning sensation.

Could Plegridy cause Burning sensation?

Among these 92 people:

How long have people been on Plegridy when they have Burning sensation? *

  • < 1 month: 47.62 %
  • 1 - 6 months: 14.29 %
  • 6 - 12 months: 9.52 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 19.05 %
  • 5 - 10 years: 9.52 %
  • 10+ years: 0.0 %

What is the gender of people who have Burning sensation when taking Plegridy? *

  • female: 87.78 %
  • male: 12.22 %

What is the age of people who have Burning sensation when taking Plegridy? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.72 %
  • 20-29: 1.72 %
  • 30-39: 17.24 %
  • 40-49: 18.97 %
  • 50-59: 36.21 %
  • 60+: 24.14 %

What are other drugs people take besides Plegridy? *

  1. Ampyra: 15 people, 16.30%
  2. Avonex: 12 people, 13.04%
  3. Copaxone: 11 people, 11.96%
  4. Tecfidera: 11 people, 11.96%
  5. Vitamin D: 10 people, 10.87%
  6. Vitamin D3: 6 people, 6.52%
  7. Valium: 5 people, 5.43%
  8. Ocrevus: 4 people, 4.35%
  9. Vitamin B12: 4 people, 4.35%
  10. Ambien: 4 people, 4.35%

What are other side effects people have besides Burning sensation? *

  1. Hypoaesthesia (reduced sense of touch or sensation): 28 people, 30.43%
  2. Fatigue (feeling of tiredness): 26 people, 28.26%
  3. Pain: 24 people, 26.09%
  4. Weakness: 23 people, 25.00%
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 23 people, 25.00%
  6. Influenza Like Illness: 22 people, 23.91%
  7. Pain In Extremity: 19 people, 20.65%
  8. Headache (pain in head): 18 people, 19.57%
  9. Gait Disturbance: 17 people, 18.48%
  10. Injection Site Erythema (redness at injection site): 17 people, 18.48%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 86 people, 93.48%
  2. Gait Disturbance: 13 people, 14.13%
  3. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 6.52%
  4. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 4 people, 4.35%
  5. Iron Deficiency: 4 people, 4.35%
  6. Stress And Anxiety: 3 people, 3.26%
  7. Red Blood Cell Count Increased: 2 people, 2.17%
  8. High Blood Pressure: 2 people, 2.17%
  9. High Blood Cholesterol: 2 people, 2.17%
  10. Skin Infection: 1 person, 1.09%

* Approximation only. Some reports may have incomplete information.

Do you take Plegridy and have Burning sensation?

- Check whether Burning sensation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Plegridy:

Burning sensation treatments and more:

How severe was Burning sensation and when was it recovered:

Expand to all the drugs that have ingredients of peginterferon beta-1a:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plegridy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Burning sensation:

Browse all the conditions that are associated with Burning sensation:


How the study uses the data?

The study uses data from the FDA. It is based on peginterferon beta-1a (the active ingredients of Plegridy) and Plegridy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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