Plegridy and Therapeutic response unexpected - a phase IV clinical study of FDA data

Summary:

Therapeutic response unexpected is reported as a side effect among people who take Plegridy (peginterferon beta-1a), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Ampyra, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Therapeutic response unexpected when taking Plegridy. It is created by eHealthMe based on reports of 14,748 people who have side effects when taking Plegridy from the FDA, and is updated regularly.

What is Plegridy?

Plegridy has active ingredients of peginterferon beta-1a. eHealthMe is studying from 14,764 Plegridy users. Check the latest studies of Plegridy.

What is Therapeutic response unexpected?

Therapeutic response unexpected is found to be associated with 1,419 drugs and 1,554 conditions by eHealthMe. Check the latest studies of Therapeutic response unexpected.

On Jul, 19, 2026

14,748 people reported to have side effects when taking Plegridy.
Among them, 19 people (0.13%) have Therapeutic response unexpected.

Could Plegridy cause Therapeutic response unexpected?

Among these 19 people:

How long have people been on Plegridy when they have Therapeutic response unexpected? *

What is the gender of people who have Therapeutic response unexpected when taking Plegridy? *

female: 63.16 %
male: 36.84 %

What is the age of people who have Therapeutic response unexpected when taking Plegridy? *

What are other drugs people take besides Plegridy? *

What are other side effects people have besides Therapeutic response unexpected? *

Insomnia (sleeplessness): 6 people, 31.58%
Gait Disturbance: 6 people, 31.58%
Weakness: 6 people, 31.58%
High Blood Pressure: 6 people, 31.58%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 31.58%
Pain: 5 people, 26.32%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 26.32%
White Blood Cell Count Decreased: 5 people, 26.32%
Dizziness: 4 people, 21.05%
Headache (pain in head): 4 people, 21.05%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 19 people, 100.00%
Gait Disturbance: 13 people, 68.42%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 15.79%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 15.79%
Pain: 2 people, 10.53%
Neuralgia (pain in one or more nerves): 2 people, 10.53%
Muscle Spasms (muscle contraction): 2 people, 10.53%
Insomnia (sleeplessness): 2 people, 10.53%
High Blood Pressure: 2 people, 10.53%
Fatigue (feeling of tiredness): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Plegridy and have Therapeutic response unexpected?

- Check whether Therapeutic response unexpected is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Plegridy:

Plegridy (14,764 reports)

Browse all side effects of Plegridy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Therapeutic response unexpected:

Therapeutic response unexpected (1,419 drugs)

Browse all the conditions that are associated with Therapeutic response unexpected:

Therapeutic response unexpected (1,554 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on peginterferon beta-1a (the active ingredients of Plegridy) and Plegridy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.