Plendil and Cervical myelopathy - a phase IV clinical study of FDA data

Summary:

Cervical myelopathy is reported as a side effect among people who take Plendil (felodipine), especially for people who are 60+ old, also take Invanz, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Cervical myelopathy when taking Plendil. It is created by eHealthMe based on reports of 4,897 people who have side effects when taking Plendil from the FDA, and is updated regularly.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

What is Cervical myelopathy?

Cervical myelopathy (clinical syndrome characterized by clumsiness in hands; gait imbalance; caused by compression of the spinal cord) is found to be associated with 118 drugs and 217 conditions by eHealthMe. Check the latest studies of Cervical myelopathy.



On Jul, 16, 2026

4,897 people reported to have side effects when taking Plendil.
Among them, 15 people (0.31%) have Cervical myelopathy.

Could Plendil cause Cervical myelopathy?

Among these 15 people:

What is the age of people who have Cervical myelopathy when taking Plendil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Plendil? *

  1. Zyrtec: 15 people, 100.00%
  2. Nystatin: 15 people, 100.00%
  3. Nabumetone: 15 people, 100.00%
  4. Mobic: 15 people, 100.00%
  5. Zometa: 15 people, 100.00%
  6. Lortab: 15 people, 100.00%
  7. Lisinopril: 15 people, 100.00%
  8. Lasix: 15 people, 100.00%
  9. Ketoconazole: 15 people, 100.00%
  10. Invanz: 15 people, 100.00%

What are other side effects people have besides Cervical myelopathy? *

  1. Wound Infection Staphylococcal: 15 people, 100.00%
  2. Hepatomegaly (abnormal enlargement of the liver): 15 people, 100.00%
  3. Fistula Discharge (discharge from abnormal passage of structure/organ): 15 people, 100.00%
  4. Gallstones (stone formation by bile component): 15 people, 100.00%
  5. Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs): 15 people, 100.00%
  6. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 15 people, 100.00%
  7. Headache (pain in head): 15 people, 100.00%
  8. Heart Valve Incompetence (heart's valves do not work correctly): 15 people, 100.00%
  9. Hepatic Enzyme Increased: 15 people, 100.00%
  10. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 15 people, 100.00%

What are the existing conditions these people have? *

  1. Trismus (reduced opening of the jaws): 15 people, 100.00%
  2. Multiple Myeloma (cancer of the plasma cells): 15 people, 100.00%
  3. Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Plendil and have Cervical myelopathy?

- Check whether Cervical myelopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Plendil:

Cervical myelopathy treatments and more:

How severe was Cervical myelopathy and when was it recovered:

Expand to all the drugs that have ingredients of felodipine:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plendil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cervical myelopathy:

Browse all the conditions that are associated with Cervical myelopathy:


How the study uses the data?

The study uses data from the FDA. It is based on felodipine (the active ingredients of Plendil) and Plendil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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