Ponstel and Diarrhea - a phase IV clinical study of FDA data

Summary:

Diarrhea is reported as a side effect among people who take Ponstel (mefenamic acid), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lyrica, and have Hypopharyngeal cancer.

The phase IV clinical study analyzes which people have Diarrhea when taking Ponstel. It is created by eHealthMe based on reports of 398 people who have side effects when taking Ponstel from the FDA, and is updated regularly.

What is Ponstel?

Ponstel has active ingredients of mefenamic acid. It is often used in pain. eHealthMe is studying from 453 Ponstel users. Check the latest studies of Ponstel.

What is Diarrhea?

Diarrhea is found to be associated with 3,720 drugs and 5,754 conditions by eHealthMe. Check the latest studies of Diarrhea.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 26, 2026

398 people reported to have side effects when taking Ponstel.
Among them, 16 people (4.02%) have Diarrhea.

Among these 16 people:

How long have people been on Ponstel when they have Diarrhea? *

What is the gender of people who have Diarrhea when taking Ponstel? *

female: 81.25 %
male: 18.75 %

What is the age of people who have Diarrhea when taking Ponstel? *

What are other drugs people take besides Ponstel? *

Lyrica: 4 people, 25.00%
Inderal: 3 people, 18.75%
Yasmin: 3 people, 18.75%
Erbitux: 3 people, 18.75%
Lithium Carbonate: 3 people, 18.75%
Zyrtec: 2 people, 12.50%
Clorazepate Dipotassium: 2 people, 12.50%
Fluvoxamine Maleate: 2 people, 12.50%
Lasix: 2 people, 12.50%
Levothyroxine Sodium: 2 people, 12.50%

What are other side effects people have besides Diarrhea? *

Abdominal Distension: 5 people, 31.25%
Nausea And Vomiting: 5 people, 31.25%
Hypotension (abnormally low blood pressure): 5 people, 31.25%
Constipation: 5 people, 31.25%
Anaemia (lack of blood): 4 people, 25.00%
Suicide Attempt: 4 people, 25.00%
Pitting Oedema (skin discoloration): 3 people, 18.75%
Abdominal Pain Upper: 3 people, 18.75%
Multiple Drug Overdose: 3 people, 18.75%
Headache (pain in head): 3 people, 18.75%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 18.75%
Diabetes: 3 people, 18.75%
High Blood Pressure: 3 people, 18.75%
Insomnia (sleeplessness): 3 people, 18.75%
Hypopharyngeal Cancer: 3 people, 18.75%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 12.50%
Abdominal Pain: 2 people, 12.50%
Acne (skin problems that cause pimples): 2 people, 12.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 12.50%
Bipolar Disorder (mood disorder): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Ponstel and have Diarrhea?

- Check whether Diarrhea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ponstel:

Ponstel (453 reports)

Diarrhea treatments and more:

Diarrhea (756,291 reports)

Browse all side effects of Ponstel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diarrhea:

Diarrhea (3,720 drugs)

Browse all the conditions that are associated with Diarrhea:

Diarrhea (5,754 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mefenamic acid (the active ingredients of Ponstel) and Ponstel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.