Posaconazole and Acute hepatic failure - a phase IV clinical study of FDA data

Summary:

Acute hepatic failure is reported as a side effect among people who take Posaconazole (posaconazole), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Clofarabine, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Acute hepatic failure when taking Posaconazole. It is created by eHealthMe based on reports of 9,473 people who have side effects when taking Posaconazole from the FDA, and is updated regularly.

What is Posaconazole?

Posaconazole has active ingredients of posaconazole. eHealthMe is studying from 9,475 Posaconazole users. Check the latest studies of Posaconazole.

What is Acute hepatic failure?

Acute hepatic failure is found to be associated with 710 drugs and 1,185 conditions by eHealthMe. Check the latest studies of Acute hepatic failure.

On Aug, 11, 2026

9,473 people reported to have side effects when taking Posaconazole.
Among them, 14 people (0.15%) have Acute hepatic failure.

Could Posaconazole cause Acute hepatic failure?

Among these 14 people:

How long have people been on Posaconazole when they have Acute hepatic failure? *

What is the gender of people who have Acute hepatic failure when taking Posaconazole? *

female: 18.18 %
male: 81.82 %

What is the age of people who have Acute hepatic failure when taking Posaconazole? *

What are other drugs people take besides Posaconazole? *

What are other side effects people have besides Acute hepatic failure? *

Herpes Simplex (herpes simplex is a common viral infection): 7 people, 50.00%
Encephalopathy (functioning of the brain is affected by some agent or condition): 6 people, 42.86%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 6 people, 42.86%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 4 people, 28.57%
Bleeding Disorders: 4 people, 28.57%
Renal Impairment (severely reduced kidney function): 3 people, 21.43%
Drug Resistance (reduction in effectiveness of a drug): 3 people, 21.43%
Hypotension (abnormally low blood pressure): 3 people, 21.43%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 14.29%
Death: 2 people, 14.29%

What are the existing conditions these people have? *

Herpes Simplex (herpes simplex is a common viral infection): 4 people, 28.57%
Pyogenic Liver Abscess (liver abscess caused by bacteria): 4 people, 28.57%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 28.57%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 21.43%
Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 2 people, 14.29%
Bone Marrow Conditioning Regimen: 2 people, 14.29%
Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 1 person, 7.14%
Agitation (state of anxiety or nervous excitement): 1 person, 7.14%
Anal Ulcer: 1 person, 7.14%
Breast Cancer: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Posaconazole and have Acute hepatic failure?

- Check whether Acute hepatic failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Posaconazole:

Posaconazole (9,475 reports)

Browse all side effects of Posaconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute hepatic failure:

Acute hepatic failure (710 drugs)

Browse all the conditions that are associated with Acute hepatic failure:

Acute hepatic failure (1,185 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on posaconazole (the active ingredients of Posaconazole) and Posaconazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.