Potassium citrate and Fluid retention - a phase IV clinical study of FDA data

Summary:

Fluid retention is reported as a side effect among people who take Potassium citrate (potassium citrate), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Xyrem, and have Cataplexy.

The phase IV clinical study analyzes which people have Fluid retention when taking Potassium citrate. It is created by eHealthMe based on reports of 5,706 people who have side effects when taking Potassium citrate from the FDA, and is updated regularly.

What is Potassium citrate?

Potassium citrate has active ingredients of potassium citrate. It is often used in kidney stones. eHealthMe is studying from 5,909 Potassium citrate users. Check the latest studies of Potassium citrate.

What is Fluid retention?

Fluid retention (an abnormal accumulation of fluid in the blood) is found to be associated with 1,702 drugs and 2,445 conditions by eHealthMe. Check the latest studies of Fluid retention.

On May, 10, 2026

5,706 people reported to have side effects when taking Potassium citrate.
Among them, 14 people (0.25%) have Fluid retention.

Could Potassium citrate cause Fluid retention?

Among these 14 people:

How long have people been on Potassium citrate when they have Fluid retention? *

What is the gender of people who have Fluid retention when taking Potassium citrate? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Fluid retention when taking Potassium citrate? *

What are other drugs people take besides Potassium citrate? *

What are other side effects people have besides Fluid retention? *

Fall: 4 people, 28.57%
Headache (pain in head): 3 people, 21.43%
Diarrhea: 3 people, 21.43%
Oesophagitis (inflammation of oesophagus): 2 people, 14.29%
Asthma: 2 people, 14.29%
High Blood Pressure: 2 people, 14.29%
Cardiac Failure Congestive: 2 people, 14.29%
Thrombocytopenia (decrease of platelets in blood): 2 people, 14.29%
The Flu (the flu is caused by an influenza virus): 2 people, 14.29%
Swelling: 2 people, 14.29%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 35.71%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 35.71%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 28.57%
Cystinuria (formation of cystine stones in the kidneys, ureter, and bladder): 2 people, 14.29%
Multiple Myeloma (cancer of the plasma cells): 1 person, 7.14%
Haemochromatosis (body to absorb more iron than usual from food): 1 person, 7.14%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Potassium citrate and have Fluid retention?

- Check whether Fluid retention is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Potassium citrate:

Potassium citrate (5,909 reports)

Fluid retention treatments and more:

Fluid retention (79,660 reports)

Browse all side effects of Potassium citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fluid retention:

Fluid retention (1,702 drugs)

Browse all the conditions that are associated with Fluid retention:

Fluid retention (2,445 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on potassium citrate (the active ingredients of Potassium citrate) and Potassium citrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.